National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Iphigenia magnifica is a seasonal medicinal plant categorized as vulnerable and is known for colchicine alkaloids. Local healers widely use different plant parts for the treatment of rheumatism, microbial infections, and muscle-related disorders. With the increasing demand for plant-based medicine, the present investigation was designed to estimate antibacterial, antifungal, and antioxidant activities of different parts of I. magnifica. Plant extracts were obtained through Soxhlet extraction and a rotary evaporator. Fractionation was performed using various polarity solvents such as methanol, dichloromethane, ethyl acetate, n-hexane, and chloroform. The antibacterial and antifungal activities were tested using the disk diffusion method and the well diffusion method against two bacterial and three fungal strains. The DPPH free radical scavenging test was followed to measure antioxidant capability, with ascorbic acid serving as the standard. Among the different extracts, ethyl acetate showed strong antibacterial activity against S. aureus with 14.3 ± 1.20 mm zone of inhibition and E. coli with 12 ± 1.15 mm zone of inhibition. Methanolic seed extracts recorded the highest antifungal activity against P. chrysogenum with 51.0 ± 1.66 mm zone of inhibition, followed by A. niger and F. verticillioides with 42.0 ± 1.15 and 32.0 ± 1.15 mm zone of inhibition. Significant antioxidant potential was recorded in ethyl acetate extracts of seed, leaf, and corm, revealing IC?? values of 54.5 ± 0.3, 58.3 ± 0.5, and 58.6 ± 0.2 μg/mL, respectively. The output of this ethnomedicinally important I. magnifica is one of the promising sources of novel bioactive compounds for further drug design.
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