National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
A one-month-old, 30 kg calf was presented to Referral Veterinary Polyclinic ICAR-IVRI, Bareilly, with the history of anorexia, salivation, dullness, ataxia, laboured breathing and administration of bolus having a combination of fenbendazole (3000mg) and ivermectin (100mg). Clinical examination revealed pale mucous membrane, mydriasis, the absence of pupillary and menace reflex, sticky salivation, normal body temperature, tachycardia, tachypnoea, dull, depressed, sudden fall with tremors, abnormal posture and gait. Based on the history of overdosing of ivermectin drug and clinical signs presented by the animal the case was diagnosed as ivermectin toxicity. Due to the unavailability of specific antidote (picrotoxin, physostigmine) the case was managed by administration of Activated Charcoal@ 2g/kg BW PO TID, Diazepam@ 0.5 mg/kg bid up to the disappearance of clinical signs. Aggressive fluid therapy was given to the animal for three days. Supportive treatment included inj theophylline @ 6.6mg/kg BW IM, inj Vitamin B- complex with liver extract (3ml IM), inj chlorpheniramine maleate(Avil)@ 0.5mg/kg BW IM daily for five days. The slight improvement was seen in calf after three days and complete recovery after the fifth day of the treatment.
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