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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Pyogenic infections are one of the major complications of surgery and trauma. The emerging drug resistance among microorganism increases both morbidity as well as mortality in association with such infections. Thus, selection of appropriate antibiotics and its rational use plays a key role in prevention as well as treatment of these infections. The indiscriminate use of antibiotics is one of the leading cause of emergence of drug resistant pathogens. Knowledge of etiological agents of infections and their resistance pattern is necessary to stop the continued emergence of resistance. Thus, this study will help the clinician with the tool to provide safe and effective empirical therapy. The aim of the study was to determine the commonly encountered pathogens in pus samples along with their antibiogram. This study was conducted from August 2015 to January 2016 in central lab, MBS hospital kota. Pus samples received for diagnostic microbiology was processed and identified by standard protocols. Antibiotic susceptibility test was done by Kirby Bauer disc diffusion method. Out of 150 pus samples received for culture and sensitivity in the microbiology central laboratory, 120 (80%) cases yielded positive culture while 30 (20%) cases had no growth. Among the 120 culture positive pus samples, 105 yielded pure bacterial isolates and 15 yielded mixed infection. E. coli was the most common isolates followed by Staphylococcus aureus, K. pneumoniae, Pseudomonas aeruginosa, Enterococcus spp and Proteus. Among the Gram positive isolates vancomycin, linezolid and tetracycline were the most susceptible drugs whereas among the Gram negative isolates, the most susceptible drugs were meropenem, amikacin and tetracycline. Whereas among nonfermenters most effective drug was polymyxin B followed by piperacillin- tazobactam, amikacin and meropenem. Antimicrobial resistance poses challenge in treating pyogenic infections. So appropriate and rational use of antibiotic is important to avoid emergence of multidrug resistant strains.