Bacterial Aetiology and Antibiogram of Bloodstream Infections: A Retrospective Study from a Tertiary Care Centre in Navi Mumbai, India
Rita Swaminathan*, Aparna Khedkar, Ranjana Santra and Shrikrishna A. Joshi
Department of Microbiology DY Patil School of Medicine Nerul Navi Mumbai, India
*Corresponding author
Abstract:
Bloodstream infections (BSIs) are a major cause of morbidity and mortality in hospitalized patients. Early identification of causative organisms and their antimicrobial susceptibility patterns is essential for appropriate empirical therapy and infection control. To evaluate the bacterial aetiology of blood culture isolates and their antimicrobial susceptibility patterns in a tertiary care hospital. This retrospective observational study was conducted over one year (January–December 2022) and included 532 patients with positive blood cultures. Identification of isolates and antimicrobial susceptibility testing were performed using standard microbiological methods in accordance with CLSI guidelines. Out of 532 isolates, Gram-positive cocci (GPC) accounted for 55.1% and Gram-negative bacteria (GNB) for 44.9%. Among GPC, coagulase-negative staphylococci (CoNS) were predominant, with methicillin-resistant CoNS (65.2%). Among GNB, Klebsiella pneumoniae (27.2%) and Pseudomonas aeruginosa (16.7%) were most common. Methicillin-resistant isolates showed complete resistance to beta-lactam antibiotics but retained high susceptibility to vancomycin and linezolid. Gram-positive cocci were predominant in bloodstream infections, with a significant burden of antimicrobial resistance among both Gram-positive and Gram-negative isolates. Continuous surveillance and antimicrobial stewardship are essential.
Keywords: Bloodstream infection, antibiogram, antimicrobial resistance, MRSA, CoNS
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How to cite this article:
Rita Swaminathan, Aparna Khedkar, Ranjana Santra and Shrikrishna A. Joshi. 2026. Bacterial Aetiology and Antibiogram of Bloodstream Infections: A Retrospective Study from a Tertiary Care Centre in Navi Mumbai, India.
Int.J.Curr.Microbiol.App.Sci. 15(3): 229-236. doi:
https://doi.org/10.20546/ijcmas.2026.1503.024
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National Academy of Agricultural Sciences (NAAS) 
