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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
E. officinalis (Amla) enjoys a holy position in Ayurveda-an Indian indigenous system of medicine. Hence, in the current study we aimed for determination of antioxidant and antibacterial potential of Emblica officinalis (Amla). Leaves of E. officinalis was subjected to successive solvent extraction by continuous hot extraction (Soxhlet) with double distilled water. Antioxidant assay was carried out by in-vitro model using DPPH free radical scavenging activity. In-vitro antibacterial activity of aqueous (Aq.) extract of leaves of E. officinalis (Amla) was assessed using agar well diffusion method with Chloramphenicol as positive control and Dimethyl sulfoxide (DMSO) as negative control. The zones of inhibition after 48 hours of was measured in millimeters (mm). Results delineated that Aq. extract of leaves of E. officinalis (Amla) showed a dose dependent DPPH scavenging activity. Furthermore, the DPPH free radical scavenging activity of Aq. extract of leaves of E. officinalis (Amla) were comparable with that of standard ascorbic acid. In addition, Aq. extract of leaves of E. officinalis (Amla) possess potential antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Klebsella pneumoniae, and methicillin resistant Staphylococcus aureus (MRSA). In conclusion, E. officinalis could be used alternative to synthetic antioxidants and antimicrobials since Aq. extract of leaves of E. officinalis mimic the biological activities of synthetic antioxidant and antimicrobials.