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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2015 - IJCMAS--ICV 2015: 85.95 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2017) [Effective from January 1, 2017]For more details click here
Indexed in



National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2017)
[Effective from January 1, 2017]
For more details click here

ICV 2015: 85.95
Index Copernicus ICI Journals Master List 2015 - IJCMAS--ICV 2015: 85.95
For more details click here
journals IJCMAS
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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2015: 85.95
NAAS RATING 2017: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(3): 1859-1869
DOI: https://doi.org/10.20546/ijcmas.2017.603.212


A Prospective Study on the Prevalence and Antibiotic Sensitivity Pattern of Methicillin Resistant Staphylococcus aureus isolated from Various Clinical Specimen at a Tertiary Care Post Graduate Teaching Institute
Anjali Kulshrestha1*, V. Anamika2, K. Mrithunjay2, V. Himanshu3, K.Manish4 and A.S Dalal2
1Department of Microbiology, NIMS, Shobha nagar, Jaipur, Rajasthan, India
2Department of Microbiology, GMCH, Udaipur, India
3Departmen of Anaesthesia and Critical Care, SRMS-IMS, Bareilly, India
4DNB, Apollo, New Delhi, India
*Corresponding author
Abstract:

In recent times, the treatment of Staphylococcus aureus infection has become problematic because of emergence of resistance to antibiotics which is a cause of concern for all the clinicians and microbiologists worldwide. Infections caused by MRSA have been associated with high morbidity and mortality rates. Hence this study was conducted to know the prevalence of Methicillin resistant Staphylococcus aureus [MRSA] isolates in various clinical specimens and to determine the sensitivity of these isolates to different antimicrobial agents. Among the 161 clinical isolates of S. aureus, highest isolation was from pus samples (64%), followed by blood (13%) and respiratory secretions (13%). 82 (51%) were identified as MRSA by Cefoxitin disc diffusion method and maximum MRSA were again isolated from pus (61%). Comparatively MRSA prevalence is more in males (73%) and most common affected age group was 21-30 years. All MRSA strains were resistant to penicillin (100%), followed by ciprofloxacin (93%) and erythromycin (61%). We found statistically significant differences in the drug susceptibility pattern of MRSA & MSSA for Penicillin, Clindamycin, Erythromycin, Ciprofloxacin, Co-trimoxazole and Levofloxacin. MDR-MRSA strains in our study are 45%. Hence we suggest, more and more studies in future are needed to fight against rising menace of antibiotic resistance among Staphylococcus aureus


Keywords: MSSA, MRSA, Multidrug resistance
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How to cite this article:

Anjali Kulshrestha, V. Anamika, K. Mrithunjay, V. Himanshu, K. Manish and Dalal, A.S. 2017. A Prospective Study on the Prevalence and Antibiotic Sensitivity Pattern of Methicillin Resistant Staphylococcus aureus isolated from Various Clinical Specimen at a Tertiary Care Post Graduate Teaching Institute.Int.J.Curr.Microbiol.App.Sci. 6(3): 1859-1869. doi: https://doi.org/10.20546/ijcmas.2017.603.212