International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 5, Issue:10, October, 2016

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(10): 533-536

Efficacy of Procalcitonin as a Marker of Acute Inflammation in Patients of Suspected Bacterial Sepsis
Tariq Ahmad Shah*, Vidya Pai and Jitendra Chandra Devrari
Department of Microbiology, YMC, Mangalore, India
*Corresponding author

Bacteraemia is associated with high morbidity and mortality. Sepsis is the second most common cause of death after myocardial infarction in patients admitted to intensive care units. Time to detection and treatment decides the outcome.There is a constant exploration for biomarkers of sepsis. Aim of the present study was to determine procalcitonin levels in patients with suspected sepsis and its correlation with blood culture positivity. Blood culture and procalcitonin levels were done in 116 inpatients of our teaching hospital, which were suspected to have sepsis. Among 116 patients of suspected sepsis, 13 patients had a positive blood culture (11.20%). Procalcitonin levels of 12 of proven sepsis patients was positive (>0.5 ng/ml). The sensitivity, specificity, the PPV and the NPV of Procalcitonin were 92.85%, 95.37%, 72.22% and 99.03% respectively. Procalcitonin is a promising biomarker in sepsis. Especially the high negative predictive value of PCT, can avoid unwarranted use of antibiotics.

Keywords: Procalcitonin, Sepsis,Blood culture,Bacterial Sepsis

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How to cite this article:

Tariq Ahmad Shah, Vidya Pai and Jitendra Chandra Devrari. 2016. Efficacy of Procalcitonin as a Marker of Acute Inflammation in Patients of Suspected Bacterial Sepsis.Int.J.Curr.Microbiol.App.Sci. 5(10): 533-536. doi:
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.