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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(10): 282-288
DOI: http://dx.doi.org/10.20546/ijcmas.2016.510.031


Bacterial Study of CSOM and their Changing Patterns of Antibiotic Sensitivity and Resistance
Upasana Bhumbla1*, Shobha Paul2, Dinesh Raj Mathur3 and Gyaneshwari3
1AIIMS Campus, Rishikesh-249203, India
2Department of Microbiology, MNR Medical College, Sangareddy, India 3Department of Microbiology, Shadan Institute of Medical Sciences, Hyderabad, India
*Corresponding author
Abstract:

Chronic Suppurative Otitis Media is the most common childhood infectious disease worldwide. It is the most common cause of hearing impairment in the developing world, although it is infrequently seen in the developed world. It is an inflammatory condition of the ear that causes recurrent ear discharge or otorrhoea, through a perforation of the ear drum or tympanic membrane. It is also found to be the single major cause for conductive deafness, and is responsible for 1.5% speech disorders. To study the spectrum of bacterial etiological agents among patients clinically diagnosed as CSOM. This study was conducted on 105 patients of clinically diagnosed cases of CSOM attending ENT OPD. After proper sample collection by sterile aural swabs, they were immediately sent to the microbiology laboratory for aerobic bacterial culture, isolation and identification. Routine antibacterial susceptibility and detection of MRSA and ESBL was carried as per CLSI guidelines. The commonest age group affected was 10 months-10 years (28.5%) mainly affecting males (60%).Patients were mainly from rural background (81.91%) and majority of cases were reported in the months of July to September(45.7%). Out of 105 patients, Gram negative isolates were 51 (48.5%) and Gram positive isolates were 32 (30.4%) and remaining 17 (16.1%) showed no growth. P. aeruginosa (34.3%) was the predominant bacterial organism isolated, followed by Staphylococcus aureus (28.6%). Out of 28 isolates of S. aureus, 10 (35.7%) were MRSA and out of 18 Gram negative isolates, 5 (27.7%) were ESBL producers. Antibiogram of  isolates revealed that Amikacin was the most sensitive drug amongst all gram positive and gram negative organisms. Imipenem was the most sensitive drug among gram negative isolates whereas Vancomycin was the most sensitive drug among gram positive isolates.


Keywords: Chronic Suppurative Otitis Media (CSOM),MRSA,ESBL.
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How to cite this article:

Upasana Bhumbla, Shobha Paul, Dinesh Raj Mathur and Gyaneshwari. 2016. Bacterial Study of CSOM and their Changing Patterns of Antibiotic Sensitivity and Resistance.Int.J.Curr.Microbiol.App.Sci. 5(10): 282-288. doi: http://dx.doi.org/10.20546/ijcmas.2016.510.031