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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(10): 156-165
DOI: http://dx.doi.org/10.20546/ijcmas.2016.510.018


Study of Candida Colonization and Candidemia in Neonates Admitted in Neonatal Intensive Care Unit at a Tertiary Care Institute of Bikaner, Rajasthan, India
Kavita Bansiwal1, Abhishek Binnani1 and Priyanka Soni Gupta2*
1Department of Microbiology, S. P. Medical College, Bikaner, Rajasthan,
2Department of Microbiology, Jawahar Lal Nehru Medical College, Ajmer, Rajasthan, India
*Corresponding author
Abstract:

The incidence of colonization and infection with Candida species has risen dramatically in the past decade with high rates of carriage in neonates, especially pre-terms, attributed to the advancement in medical field, life support systems, relative immunodeficiency, extensive use of broad spectrum antibiotics. Therefore we conducted this study to determine the colonization and candidemia in neonates admitted to neonatal intensive care unit along with its risk factors and possible maternal and nosocomial source. Isolated candida species was identified and their susceptibility to different antifungal agent determined. This study was carried out in the Department of Microbiology, S.P. Medical College from March 2012 to March 2013 on a total of  2132 samples collected from neonates admitted to neonatal intensive care unit of department of paediatric and labour room, P.B.M. Hospital, Bikaner, Vaginal swabs from pregnant women, swabs from hands of  health care staff  in NICU & from nasogastric tube and iv line. Candida colonization rate was 47.31% in neonates admitted to NICU, more frequently in preterm neonates with IV antibiotics. Candidemia was 11.1% in neonates of NICU. Candida albicans was the most common species causing colonization and Candidemia.  All candida species were susceptible to all antifungal agents except Candida krusei & Candida glabrata which were highly resistant to Fluconazole.  I.V. antibiotics, preterm neonates, low birth weight, RDS, Ventilation therapy and prior Candida colonization were identified as significant risk factors. Candida Parapsilosis is an emerging fungal pathogen and incidence of infection caused by it may continue to rise.


Keywords: Candida,preterm neonate, antifungal agent candidemia.
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How to cite this article:

Kavita Bansiwal, Abhishek Binnani and Priyanka Soni Gupta. 2016. Study of Candida Colonization and Candidemia in Neonates Admitted in Neonatal Intensive Care Unit at a Tertiary Care Institute of Bikaner, Rajasthan, IndiaInt.J.Curr.Microbiol.App.Sci. 5(10): 156-165. doi: http://dx.doi.org/10.20546/ijcmas.2016.510.018