National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Tubercular Meningitis (TBM) is an endemic disease in developing countries. Adenosine deaminase activity (ADA) has been of great importance for many years in TBM diagnosis. The present study has been undertaken to assess the levels of CSF-ADA activity in different types of meningitis patients, diagnosed as per clinical and other findings (CSF- Cell Count and Types and.CSF Protein and Sugar content) in comparison to Control group, who are to be considered as other than those with meningitis based on clinical and CSF studies. In total, 98 CSF samples were collected from different groups of patients comprising different types of meningitis (Aseptic, Pyogenic, Tubercular, Fungal and Control groups, consisting of 22 patients in each group excepting Fungal Meningitis group having 10 patients. The control group consisted of 22 people without Meningitis. CSF ADA activity was found to be significantly higher (30 IU/L with a mean of 20.99 + 4.66) in tubercular meningitis in comparison to other groups of meningitis. Other cases & the control group showed ADA concentration of 1.36 + 0.59 IU/L. The present Study also reveals that CSF ADA concentration was found to be < 5 IU/L in control group.
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