International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 5, Issue:10, October, 2016

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(10): 20-26

Antimicrobial Activity of Guggulsterone E and Z
Pramod Kumar Sairkar1*, Anjana Sharma2 and N.P. Shukla3
1Centre of Excellence in Biotechnology, M.P. Council of Science & Technology,
Bhopal, Madhya Pradesh, India
2Bacteriology Laboratory, Department of Post Graduate Studies & Research in Biological Science, Rani Durgawati University, Jabalpur Madhya Pradesh, India
3Madhya Pradesh Pollution Control Board, Bhopal, Madhya Pradesh, India
*Corresponding author

Guggulsterone is a main active compound of gum guggul, which has commonly used as ant-inflammatory, hepatoprotective, muscle relaxing, anti-arthritic, hy-polipidemic, hypocholestrolemic and anti-obesity. In the present study, its antimicrobial activity of guggulsterone E and Z against five microorganisms i.e. Escherichia coli (Wild), E. Cole (DH5α), Micrococcus luteus, Staphylococcus aureus and Bacillus subtilis were undertaken. Disc diffusion method was used for antimicrobial activity assessment of compound guggulsterone E and Z. The discs were impregnated with 100 and 200 µg per disc and exposed to culture bed of five test organism i.e. E. coli (Wild), E. coli (DH5α), M. luteus, S. aureus and B. subtilis. After 24 hours of incubation at 37 °C, it was observed that the guggulsterone E and Z did not show any inhibition zone against the all five test organisms.

Keywords: Guggulsterone E and Z, Antimicrobial activity, E. coli, M.luteus, S.aureus, B.subtilis.

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How to cite this article:

Pramod Kumar Sairkar, Anjana Sharma, N.P. Shukla. 2016. Antimicrobial Activity of Guggulsterone E and Z.Int.J.Curr.Microbiol.App.Sci. 5(10): 20-26. doi:
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.