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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(2): 86-91
DOI: http://dx.doi.org/10.20546/ijcmas.2016.502.009


Respiratory Syncytial Virus – Detection, Prevalence and Usefulness in Clinical Management: A hospital based study
Kiran Yadav1, VG Ramachandran1, Shukla Das1 and Dheeraj Shah2
1Department of Microbiology, UCMS & GTB Hospital, Delhi, India
2Department of Pediatrics, UCMS & GTB Hospital, Delhi, India
*Corresponding author
Abstract:

Acute respiratory tract infections (ARTIs) play a major role in hospitalizations of children, and Respiratory syncytial virus (RSV) is well recognized as the most important pathogen causing ARTI. This study aimed to evaluate the epidemiological and clinical patterns of RSV infection in children hospitalized for lower respiratory tract infections (LRTI) in tertiary care hospital in East Delhi, India. A nasopharyngeal aspirate was obtained for detection of RSV in all cases. Sociodemographic data, clinical signs, diagnosis and hospital admissions were documented. Total 130 cases with LRTI between 2 months to 5 years of age were included in the study. Flocked nasal swabs samples were processed for detection of RSV virus by both rapid antigen detection method and RT-PCR. RSV infection was found in 14 out of 130 patients (10.8%). Among the 14 children with RSV infection, nine patients (90%) were under 12 months of age. The main clinical manifestations of RSV infection were chest wall retraction (100%) and wheezing (78%). This study indicates that RSV is an important cause of respiratory tract infection in infants and young children and the imperative need for rapid and reliable screening test to detect RSV infection for avoiding unjustified use of antibiotics.


Keywords: Respiratory syncytial virus, Respiratory tract infection, Reverse Transcription Polymerase Chain Reaction
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How to cite this article:

Kiran Yadav, VG Ramachandran, Shukla Das and Dheeraj Shah. 2016. Respiratory Syncytial Virus – Detection, Prevalence and Usefulness in Clinical Management: A hospital based studyInt.J.Curr.Microbiol.App.Sci. 5(2): 86-91. doi: http://dx.doi.org/10.20546/ijcmas.2016.502.009