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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020]For more details click here

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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(7): 3568-3574
DOI: https://doi.org/10.20546/ijcmas.2018.707.415


Cell Mediated Immunity Dysfunction Retrieval Using the Extracts of the Plant Cassytha capillaries (Meissen)
A.J.A. Ranjitsingh1, C. Padmalatha1, G. Athinarayanan2 and P. Dhasarathan3
1UGC Emeritus Fellow
2Department of Microbiology, Sri Ram Nallamani Yadava College of Arts and Science, Tenkasi, India
3Department of Biotechnology, Prathyusha Engineering College, Chennai, India
*Corresponding author
Abstract:

The growing incidence of infectious diseases, autoimmune problems and tumour formation are due to the weakness/dysfunction of immune system. Many xenobiotic components that enter human system through food, air and food chain interferes with the functioning of cells and secretions that offer immunity. Pesticides that are being indiscriminately applied get into the human system had been reported to affect the functioning of immune system. To validate this information, in the present study a commonly used organophosphorus pesticide Quinolphos was administered to Swiss albino mice and the functioning of cell mediated immunity was measured using Delayed Type Hyper Sensitivity Reaction (DTH) using sheep red blood cells as a challenging antigen. The pesticide induced a reduction in DTH response. So to improve the DTH dysfunction remedial measures were tried using Standard immune boosting drugs and the extract of a plant Cassytha capillaries. The remediating agents were found to retrieve the lost immunity to a significant level.


Keywords: Immunity, Immunity booster, Natural products, DTH, Cassaytha capillaries
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How to cite this article:

Ranjitsingh, A.J.A., C. Padmalatha, G. Athinarayanan and Dhasarathan, P. 2018. Cell Mediated Immunity Dysfunction Retrieval Using the Extracts of the Plant Cassytha capillaries (Meissen).Int.J.Curr.Microbiol.App.Sci. 7(7): 3568-3574. doi: https://doi.org/10.20546/ijcmas.2018.707.415