National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The growing incidence of infectious diseases, autoimmune problems and tumour formation are due to the weakness/dysfunction of immune system. Many xenobiotic components that enter human system through food, air and food chain interferes with the functioning of cells and secretions that offer immunity. Pesticides that are being indiscriminately applied get into the human system had been reported to affect the functioning of immune system. To validate this information, in the present study a commonly used organophosphorus pesticide Quinolphos was administered to Swiss albino mice and the functioning of cell mediated immunity was measured using Delayed Type Hyper Sensitivity Reaction (DTH) using sheep red blood cells as a challenging antigen. The pesticide induced a reduction in DTH response. So to improve the DTH dysfunction remedial measures were tried using Standard immune boosting drugs and the extract of a plant Cassytha capillaries. The remediating agents were found to retrieve the lost immunity to a significant level.
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