National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The objective is to the study the Interactions between thyroid hormones and kidney functioning may coexist. The aim of this study was to investigate the renal function status in perimenopausal women with hypothyroidism. Total 60 perimenopausal women (30 cases and 30 controls) were recruited for the study. Thyroid hormones including thyroid stimulating hormone, thyroxin, and triiodothyronine were estimated by means of enzyme-linked immunosorbent assay. Renal functions test including (blood urea, creatinine, uric acid, and electrolytes) were investigated by a spectrophotometric method and ion selective electrolyte respectively. Significant results were obtained in this study. There was an increased concentration of blood urea, serum creatinine and uric acid in patients with hypothyroidism when compared to control. The results were statistically significant (<0.05) except urea. While in case of electrolytes there was a significantly (<0.01) decreased concentration of calcium and sodium in hypothyroidism women. There was positively significant (<0.05) association observed between TSH and parameters of renal function test including urea, serum creatinine and serum uric acid. Thyroid hormones play an important role in renal physiology and its functioning. The altered concentration of these hormones in patients with hypothyroidism may develop kidney disease which may progress with the progression of the disease.
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