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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(7): 2641-2645
DOI: https://doi.org/10.20546/ijcmas.2018.707.310


The Assessment of Renal Function Test in Perimenopausal Middle Aged Women with Hypothyroidism
Richa Jain1, Gaurav Gupta1*, Preeti Sharma2 and Pradeep Kumar2
1Department of Biochemistry, Government Medical College, Badaun, India 
 2Department of Biochemistry, Santosh Medical College & Hospital, Ghaziabad, India
Tutor, Department of Biochemistry, Government Medical College, Badaun-243601,Uttar Pradesh, India
 
*Corresponding author
Abstract:

The objective is to the study the Interactions between thyroid hormones and kidney functioning may coexist. The aim of this study was to investigate the renal function status in perimenopausal women with hypothyroidism. Total 60 perimenopausal women (30 cases and 30 controls) were recruited for the study. Thyroid hormones including thyroid stimulating hormone, thyroxin, and triiodothyronine were estimated by means of enzyme-linked immunosorbent assay. Renal functions test including (blood urea, creatinine, uric acid, and electrolytes) were investigated by a spectrophotometric method and ion selective electrolyte respectively. Significant results were obtained in this study. There was an increased concentration of blood urea, serum creatinine and uric acid in patients with hypothyroidism when compared to control. The results were statistically significant (<0.05) except urea. While in case of electrolytes there was a significantly (<0.01) decreased concentration of calcium and sodium in hypothyroidism women. There was positively significant (<0.05) association observed between TSH and parameters of renal function test including urea, serum creatinine and serum uric acid. Thyroid hormones play an important role in renal physiology and its functioning. The altered concentration of these hormones in patients with hypothyroidism may develop kidney disease which may progress with the progression of the disease.


Keywords: Hypothyroidism, Perimenopause, Creatinine
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How to cite this article:

Richa Jain, Gaurav Gupta, Preeti Sharma, Pradeep Kumar. 2018. The Assessment of Renal Function Test in Perimenopausal Middle Aged Women with HypothyroidismInt.J.Curr.Microbiol.App.Sci. 7(7): 2641-2645. doi: https://doi.org/10.20546/ijcmas.2018.707.310