International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 7, Issue:7, July, 2018

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(7): 1204-1209

Kinetics of Immune Response of Indian Major Carps to Sheep Red Blood Cells (SRBC)
B. Kalita1, Hemanta Pokhrel1*, C.V. Mohan2 and K.M. Shankar3
1College of Fisheries, Raha, Assam, India
2World Fish, NACA, India
3College of Fisheries, Mangalore, India
*Corresponding author

The kinetics of primary and secondary immune response of Indian major carps, Catla catla, Labeo rohita and Cirrhinus mrigala to sheep red blood cells (SRBC)were studied in detail at three different age groups of 120,150 and 270 days old. Fish were immunized by injection (i.m) with 106 cells/fish of SRBC suspension. The second injection was given at 20 days after the first injection with same dose. All age groups of each species produced detectable humoral antibody titers on 6th days after the first injection. Higher age groups produced higher antibody titers after first as well as second injection. The peak antibody titer was recorded on 9th days after first injection and on 7th day after second injection. The minimum level of antibody titers was recorded on 20th day after first and on 28th day after second injection. The secondary antibody titers were higher to that of the primary antibody titers produced in all three species. The level of antibody titers increased with the age within the species and was significant (p<0.05). Catla produced higher antibody titers compared to rohu and mrigal after both first and second injection.

Keywords: Indian major carps, Antibody titers, Sheep red blood cells

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How to cite this article:

Kalita, B., Hemanta Pokhrel, C.V. Mohan and Shankar, K.M. 2018. Kinetics of Immune Response of Indian Major Carps to Sheep Red Blood Cells (SRBC).Int.J.Curr.Microbiol.App.Sci. 7(7): 1204-1209. doi:
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