National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Aim of the study is to prospectively examine the Bacteriology of Chronic Rhinosinusitis at MNR Medical College & Hospital, Sangareddy, and to evaluate the antibiotic sensitivity pattern, and to discuss an empirical basis for the initial choice of the appropriate antibiotic. 217 suspected patients were included in the study. The relevant clinical details of the patients including the co-morbidities in the medical records were examined. Samples like nasal swabs collected during nasal endoscopy under sterile conditions, sinus washings, allergic mucin, tissue biopsy from polyps and tissue biopsy taken from sinus mucosa during nasal surgery, were processed and examined by Microbiology culture using recommended techniques. The antibiotic susceptibility testing was done. Out of 217 patients studied, 131 patients had positive bacterial isolates. Among the isolates Staphylococcus aureus were 32 in number which was the highest followed by Coagulase negative Staphylococci which were 25 in number. Among 131 bacterial isolates, 63 were Gram positive cocci, and were sensitive to most of the common antibiotics like aminoglycosides, amoxicillin, 2nd and 3rd generation cephalosporins. 68 were Gram negative bacilli, and the antibiotic sensitivity was more for amoxicillin, 2nd and 3rd generation cephalosporins and fluoroquinolones. Antibiotic resistance for the common isolates found in CRS ranged from 0-50%. Bacteriological profile of Chronic Rhinosinusitis at MNR Medical College, Sangareddy was thus evaluated. Hence, it is suggested that culture directed therapy is the gold standard for the management of CRS. If empirical antimicrobial therapy is used to treat CRS, it should be directed against Staphylococcus aureus, CONS and Klebsiella.
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