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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(6): 2537-2544
DOI: https://doi.org/10.20546/ijcmas.2018.706.299


Antimicrobial Susceptibility Pattern among Aerobic Gram Negative Bacilli of Lower Respiratory Tract Specimens of a Tertiary Care Hospital in Southern Rajasthan, India
Manjula J. Barbriya and Neelam Chauhan*
Department of Microbiology, Pacific institute of Medical Science (PIMS),Udaipur, Rajasthan, India
*Corresponding author
Abstract:

Lower Respiratory tract infections (LRTI’s) are the most frequent infections among patients. The consequences of increased drug resistance are far reaching since bacterial infection of the respiratory tract (RT) is a major cause of death from infectious disease. The present study was conducted to determine the bacterial etiology and their antimicrobial susceptibility pattern of Gram negative bacteria in lower respiratory tract infections so as to update the clinicians in the various antimicrobial alternatives available in the treatment. Patients with lower respiratory tract infections were collected in time span of six months. Bacterial pathogens were isolated from sputum and tracheal specimens, and subjected to antibiotic susceptibility testing, using standard bacteriologic techniques. Out of samples obtained from 442 patients, 150 (33.93%) were culture positive. 315 samples yielded no growth. 127 were Gram-negative bacilli (GNB-28.73%). 23 were Gram positive cocci. The common GNB isolates were non-fermentative gram-negative bacilli Pseudomonas aeruginosa (34.64%), followed by Klebsiella spp. (31.49 %) and Acinetobacter spp. (15.74%). GNB isolates from sputum and endotracheal aspirates were 85 (66.92 %) and 42 (33.07 %) respectively. Maximum no. of patients were from 46-60 age group (35.43 %) followed by 61-75 age group (25.98%).Gram negative isolates showed high susceptibility with Colistin, Imipenem, Ciprofloxacin, Gentamicin, Levofloxacin, Amikacin. For effective management of LRTIs bacteriological diagnosis and antibiotic susceptibility pattern is indispensable.


Keywords: Antibiotic susceptibility, Gram-negative bacteria, Lower respiratory tract infection
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How to cite this article:

Manjula J. Barbriya and Neelam Chauhan. 2018. Antimicrobial Susceptibility Pattern among Aerobic Gram Negative Bacilli of Lower Respiratory Tract Specimens of a Tertiary Care Hospital in Southern Rajasthan.Int.J.Curr.Microbiol.App.Sci. 7(6): 2537-2544. doi: https://doi.org/10.20546/ijcmas.2018.706.299