International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 7, Issue:6, June, 2018

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(6): 2446-2456

Antimicrobial Susceptibility Profile from Patients with Blood Stream Infections at a Tertiary Care Level Super Speciality Institute in Northern India
Manodeep Sen, Vikramjeet Singh, Gaurav Kumar, Rachana Kanaujia,Vineeta Mittal and Anupam Das*
Department of Microbiology, Dr Ram Manohar Lohia Institute of Medical Sciences,Lucknow, India
*Corresponding author

Globally, the frequency of bloodstream infections, their epidemiology, invading organisms & antimicrobial susceptibility pattern are always changing and giving rise to new resistance with every passing year. To study the frequency & antimicrobial susceptibility pattern of bacterial pathogens causing bloodstream infections in patients attending tertiary care super speciality institute of Northern India. This was a retrospective clinical-laboratory based study carried over two year period from January 2015 to December 2016 at tertiary health care centre. Blood samples collected from clinically suspected cases of bacteraemia were processed through automated Versa Trek blood culture system. The samples yielding positive growth were further analysed to identify the pathogen & their antimicrobial susceptibility. Overall blood culture positivity were 15.07% in 2015 & 18.45% in 2016. Gram positive bacteria predominated amongst the all bacterial isolates, of which Coagulase negative Staphylococcus were 37.69% in 2015 & 38.73% in 2016.Amongst gram negative bacteria Escherichia coli was the major isolate being 11.57% in 2015 & 13.02% in 2016. Gram positive bacteria showed maximum resistant to Penicillin, while gram negative bacteria showed maximum resistance to third generation Cephalosporins. The resistance to antimicrobials in particular to gram negative bacteria is of grave concern and measures to counteract this menace needs to be in place urgently. The findings in our study will help the clinicians to formulate proper empirical therapy for management of patients with bloodstream infections.

Keywords: Blood stream infections, Antimicrobial Susceptibility Profile

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How to cite this article:

Manodeep Sen, Vikramjeet Singh, Gaurav Kumar, Rachana Kanaujia, Vineeta Mittal and Anupam Das. 2018. Antimicrobial Susceptibility Profile from Patients with Blood Stream Infections at a Tertiary Care Level Super Speciality Institute in Northern India.Int.J.Curr.Microbiol.App.Sci. 7(6): 2446-2456. doi:
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