International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 7, Issue:6, June, 2018

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(6): 2136-2155

Screening for Helicobacter pylori Infection among Asymptomatic University Students in Alexandria, Egypt, Using Non Invasive Laboratory Techniques
Hadir EL-Kady*
Department of Microbiology and immunology, Department of Medical Laboratory Technology, Faculty of Allied Medical Sciences, Pharos University, Alexandria, Egypt
*Corresponding author

Globally, Helicobacter pylori (H. pylori) is becoming an increasingly troublesome economic and public health problem. Over 50% of the world’s population was estimated to harbor H. pylori in the upper gastrointestinal tract (GIT) and over 80% of them reside in developing nations. Unless treated, colonization persists lifelong where H. pylori presents a key factor in the etiology of GIT diseases; ranging from asymptomatic chronic gastritis up to gastric carcinoma. Therefore, accurate and timely diagnosis is the first step to address this burdensome problem. The aim of this descriptive-cross sectional study was to compare two non-invasive techniques for the diagnosis of H. pylori infection among university students. Stool and serum samples were collected from one hundred asymptomatic students to detect H. pylori antigens (Ags) in stool using chromatographic immunoassay and IgG antibodies (Abs) in serum by enzyme linked immune sorbent assay (ELISA). Fifty five (55%) of tested students were positive for each of stool Ags and serum Abs. The recorded sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of the serum Ab test in relation to stool Ag test were 98.18%, 97.78%, 98.18 % and 97.78, respectively. There was very good agreement (98%) between the results of the two tests.

Keywords: Helicobacter pylori, H. pylori stool antigen, H. pylori antibodies, chromatographic immunoassay, ELISA

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How to cite this article:

Hadir EL-Kady. 2018. Screening for Helicobacter pylori Infection among Asymptomatic University Students in Alexandria, Egypt, Using Non Invasive Laboratory Techniques.Int.J.Curr.Microbiol.App.Sci. 7(6): 2136-2155. doi:
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.