International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 5, Issue:8, August, 2016

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(8): 842-851

Triggering Factors for Relapses in Steroid Sensitive Nephrotic Syndrome
Shatha Hussain Ali1*, Zainab A. twfeek M.B.Ch.B2, Nariman Fahmi Ahmed Azat3 and  Amer Abdulameer Hasan4
1College of medicine, Al- Nahrain University, Iraq
 2ImameinKadhimein Medical City, Iraq
3Assistant Prof. in Pediatircs, College of Medicine/ Baghdad University, Iraq
4Specialist in Pediatric Nephrology, FICMS Neph., Imamein Kadhimein Medical City, Iraq
*Corresponding author

Nephrotic syndrome (NS) is a chronic disorder in childhood Relapse occurs in more than two- thirds of children. Study the trigger factors of relapses in children with NS, and correlations with some demographic factors. A prospective study including 80 children with Steroid Sensitive NS, was carried out in the Pediatric Nephrology Clinic of Imamein Kadhmian Medical City from November 2012 till end of May 2013. The following data were studied: Age, Gender, Age at diagnosis of NS, Number of days to get remission, Need for hospital admission. Triggering factors are grouped as: 1. Infections which is subdivided into: Acute respiratory Infections (ARI), Urinary Tract Infections (UTI), and others 2. Incomplaint to treatment, 3. Stop treatment 4. Decrease dose. 5. Asthma attacks. 6. Change season. 7. No cause. Total number of 80 patients with NS with 228 relapses, which occurred more in males, male: female = 1.5: 1. Majority of patients were frequent relapsers 62(77.5%). Infections is the most common triggering factor (63.59%), followed by decreasing steroid dose (21.05%), stop treatment (6.14%), asthma attacks (4.82%),  incompliant to treatment (2.63%). Respiratory infection was the main infection in male with 51 relapse (65.38%), P- value < 0.001, while UTI were more in females with 40 relapses (59.70%), with P- value <0.001. Infections, asthma attacks and decreasing dose are statically significant with male gender. Only asthma attacks which compromise 15.63% of hospital admission are statically significant with P- value 0.01. Infections are the most triggering factor for relapses in SSNS. Respiratory infection was more in males while UTI were more in females. Asthma attack correlated with hospital admission.

Keywords: Nephrotic Syndrome, relapses,triggers.

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How to cite this article:

Shatha Hussain Ali, Zainab A. twfeek M.B.Ch.B, Nariman Fahmi Ahmed Azat and  Amer Abdulameer Hasan. 2016. Triggering Factors for Relapses in Steroid Sensitive Nephrotic Syndrome.Int.J.Curr.Microbiol.App.Sci. 5(8): 842-851. doi:
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