National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
Nephrotic syndrome (NS) is a chronic disorder in childhood Relapse occurs in more than two- thirds of children. Study the trigger factors of relapses in children with NS, and correlations with some demographic factors. A prospective study including 80 children with Steroid Sensitive NS, was carried out in the Pediatric Nephrology Clinic of Imamein Kadhmian Medical City from November 2012 till end of May 2013. The following data were studied: Age, Gender, Age at diagnosis of NS, Number of days to get remission, Need for hospital admission. Triggering factors are grouped as: 1. Infections which is subdivided into: Acute respiratory Infections (ARI), Urinary Tract Infections (UTI), and others 2. Incomplaint to treatment, 3. Stop treatment 4. Decrease dose. 5. Asthma attacks. 6. Change season. 7. No cause. Total number of 80 patients with NS with 228 relapses, which occurred more in males, male: female = 1.5: 1. Majority of patients were frequent relapsers 62(77.5%). Infections is the most common triggering factor (63.59%), followed by decreasing steroid dose (21.05%), stop treatment (6.14%), asthma attacks (4.82%), incompliant to treatment (2.63%). Respiratory infection was the main infection in male with 51 relapse (65.38%), P- value < 0.001, while UTI were more in females with 40 relapses (59.70%), with P- value <0.001. Infections, asthma attacks and decreasing dose are statically significant with male gender. Only asthma attacks which compromise 15.63% of hospital admission are statically significant with P- value 0.01. Infections are the most triggering factor for relapses in SSNS. Respiratory infection was more in males while UTI were more in females. Asthma attack correlated with hospital admission.
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