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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(8): 825-831
DOI: http://dx.doi.org/10.20546/ijcmas.2016.508.092


Antibiotic Susceptibility Pattern of ESBL producing Uropathogens
Ruby Naz1, Akil Hussain2, Sameena Khan3*, Mohammad Khalid Farooqui4 and A.K.Malik5
 1Demonstrator Microbiology, SHKM Govt Medical College and Hospital Nalher Mewat, India
2Assistant Professor NIMS Medical College Jaipur, India
3Demonstrator Microbiology, SHKM Govt Medical College and Hospital Nalher Mewat, India
4Senior Resident ENT, SHKM Govt Medical College and Hospital Nalher Mewat, India
5Professor and Head of Department Microbiology, SHKM Govt Medical College and Hospital Nalher Mewat, India
*Corresponding author
Abstract:

The increasing prevalence of infections caused by antibiotic-resistant bacteria makes empirical treatment of these infections difficult. We studied prevalence of ESBL and Amp C beta lactamases in 241 uropathogens and compare the antibiotic susceptibility pattern in them. In our study E coli was most common pathogen followed by pseudomonas, klebsiella. ESBL was produced by 38.58, Amp C by 12.03% and both type beta lactamases present in 3.37%.  There is significant difference in antibiotic susceptibility of ESBL producing and non producing strains ESBL and Amp C producing isolates are less susceptible to commonly used antibiotics there is significant difference in their susceptibility except Nitrofurantoin difference is not significant (p value is <0.05) which is oldest drug, now it is commonly not uses to treat UTI. Resistance to Amikacin was found to be comparatively lower in both ESBL and non-ESBL producers. Gentamicin, Chloramphenicol and Cotrimoxazol were found to be more effective on non-ESBLs as compared to ESBL producing uropathogens.


Keywords: ESBL,AMP C beta lactamases, antibiogram, uropathogen
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How to cite this article:

Ruby Naz, Akil Hussain, Sameena Khan, Mohammad Khalid Farooqui and A.K. Malik. 2016. Antibiotic Susceptibility Pattern of ESBL producing Uropathogens.Int.J.Curr.Microbiol.App.Sci. 5(8): 825-831. doi: http://dx.doi.org/10.20546/ijcmas.2016.508.092