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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(6): 1026-1031
DOI: https://doi.org/10.20546/ijcmas.2018.706.121


Uropathogens and their Susceptibility Patterns among Hospitalized Patients in a Tertiary Care Centre in Rajamahendravaram
P. Gowthami and A. Heraman Singh*
Department of Microbiology, GSL Medical College, Rajahmundry, A.P., India
*Corresponding author
Abstract:

Urinary tract infections are one of the most common hospital-acquired infections, accounting to as many as 35% of nosocomial infections. In addition, UTIs are a leading cause of gram-negative sepsis in hospitalized patients. Early diagnosis and treatment of UTIs are essential in preventing urosepsis. This study is done to become familiar with the common uropathogens along with their antimicrobial susceptibility patterns among hospitalized patients in our setup. During the study period from June 2016 to September 2017, 520 urine samples collected from hospitalized patients were processed by microscopy and bacterial culture. Bacterial growth suggestive of significant bacteriuria (> 105 CFU/ml) was identified by standard biochemical tests and subjected to antimicrobial susceptibility test. Escherichia coli (42.2%), Klebsiella sps (27.7%) and Pseudomonas sps (17.7%) were the common uropathogens isolated in this study. Others were Staphylococcus aureus, Acinetobacter sps, and Enterococcus sps. Gram negative uropathogens demonstrated highest sensitivity to imipenem, nitrofurantoin and piperacillin tazobactam combination and moderate sensitivity to gentamicin, amikacin and ciprofloxacin. Their sensitivity to commonly used antibiotics like cephalosporins, amoxiclavulanic acid was relatively poor. This study should guide our clinicians to plan effective empiric treatment regimens in the management of UTIs and control of urosepsis in hospitalized patients.


Keywords: UTIs, Gram negative uropathogens, Hospitalized patients, Antimicrobial susceptibility
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How to cite this article:

Gowthami, P. and Heraman Singh, A. 2018. Uropathogens and their Susceptibility Patterns among Hospitalized Patients in a Tertiary Care Centre in Rajamahendravaram.Int.J.Curr.Microbiol.App.Sci. 7(6): 1026-1031. doi: https://doi.org/10.20546/ijcmas.2018.706.121