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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(5): 3142-3146
DOI: https://doi.org/10.20546/ijcmas.2018.705.367


A Study of Prevalence of Hepatitis-B and Hepatitis-C Infection in Thalassemic Patients in a Tertiary Care Hospital, Jamnagar, Gujarat, India
Chandani C. Surani, Ruchi V. Shah* and Mala Sinha
Department of Microbiology, Shri M.P. Shah Government Medical College and GGG Hospital, Jamnagar, Gujarat, India
*Corresponding author
Abstract:

Thalassemia is an autosomal recessive disease causing haemolytic anaemia. The ideal treatment of these patients involves regular, 2-4 weekly blood transfusions. The major complications by this treatment are the transmission of transfusion acquired infections such as Hepatitis B virus infection, Hepatitis C virus infection, Human immunodeficiency virus infection, Syphilis, Malaria and transfusion acquired iron overload. Aim of the study is to evaluate the prevalence of Hepatitis B & C among Thalassemic patients transmitted by blood transfusion. Retrospective study was conducted in Microbiology department, Shri M.P. Shah medical college and GGG hospital, Jamnagar from January 2016 to June 2017. Patients with thalassaemia having regular blood transfusions at this hospital were enrolled. 200 serum samples were tested by using ELISA Kits for HBsAg and Anti HCV. Out of 200 patients 119(59.5%) were male and 81(40.5%) were females. Out of them 02(1%) HBsAg positive and 10(5%) Anti–HCV reactive. More sensitive screening tests, stringent donor selection and vaccinating all children at the time of induction into the thalassemia transfusion programme are required for the better control of this transfusion – transmitted infections among Thalassemia patients.


Keywords: Thalassemia, Hepatitis B, Hepatitis C, ELISA, Blood transfusion
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How to cite this article:

Chandani C. Surani, Ruchi V. Shah and Mala Sinha. 2018. A Study of Prevalence of Hepatitis-B and Hepatitis-C Infection in Thalassemic Patients in a Tertiary Care Hospital, Jamnagar, Gujarat, India.Int.J.Curr.Microbiol.App.Sci. 7(5): 3142-3146. doi: https://doi.org/10.20546/ijcmas.2018.705.367