International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 5, Issue:8, August, 2016

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(8): 514-524

Isolation of Soil Bacteria for Potential Production of Antibiotics and their Inhibitory Effect on Growth of Pathogens
Vijaykumar Biradar1*, S. Ashwini, Pooja Lachuriye2, Sadia Fatima2 and Awase Syed2
1HOD & Director, PG Studies & Research Centre in Biotechnology, Karnatak College,
Bidar-585 401, Karnataka, India
2Research scholars, Department of Biotechnology, Karnatak College, Bidar-584 401,Karnataka, India
*Corresponding author

Soil is a richest source of microorganisms. These have played a significant role in antibiotic discovery. Though, thousands of antibiotics were discovered from soil microorganisms, very few were potent or old antibiotics loss their potency or few pathogens became multiple drug resistance. To solve these problems one has to discover new antibiotics to control pathogens. Hence, selective isolation of rare microorganisms from soil may allow the discovery of new antibiotics. Therefore they were isolated and screened for antibiotic production & to find their inhibitory effects on pathogens. It was observed that, two colonies (C2 & C4) of seven antibiotic producing bacterial colonies were identified as P. aeruginosa strain-1(C2) & strain-2(C4), and remaining unknown colonies were named as C1, C3, C5, C6 & C7. Out of seven bacteria isolated, antibiotics of C1 has inhibition effect on growth of E. coli; C2 on E. coli, P. aeruginosa & S. aureus; C3 & C5 on S. aureus; C4, C6 & C7 on E . faecalis, Further, each of soil bacteria antibiotics shown varied degree of antibiotic effects on different pathogens. C4 has highest inhibitory effect of the growth of E. faecalis; followed by C5 on S. aureus and C2 on P. aeruginosa. The antibiotic effect of some selected soil bacteria, and commercial streptomycin antibiotic has almost equivalent affect on four studied pathogens.

Keywords: Soil Bacteria,Antibiotics P.aeruginosa,E. coli,E . faecalis

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How to cite this article:

Vijaykumar Biradar, S. Ashwini, Pooja Lachuriye, Sadia Fatima and Awase Syed. 2016. Isolation of Soil Bacteria for Potential Production of Antibiotics and their Inhibitory Effect on Growth of Pathogens.Int.J.Curr.Microbiol.App.Sci. 5(8): 514-524. doi:
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