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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(8): 470-478
DOI: http://dx.doi.org/10.20546/ijcmas.2016.508.050


The Role of Momordica charantia in Reducing the Level of Glucose in Mice
Maha Hameed A. Al-Bahrani*
Molecular and Medical Biotechnology Department, College of Applied Biotechnology, Al-Nahrin University, Baghdad, Iraq
*Corresponding author
Abstract:

The effects of aqueous and alcoholic extract (Momordica charantia) on the level of serum glucose were studied on 40 mature males distributed into 5 equal groups and fed basal diets. Group (1) was kept as control negative (fed on basal diet), while the other 4 groups were subcutaneously administered a single dosage of alloxan to induce experimental diabetes. Group (2) was left as a control positive group (diabetes) while the other groups (3), (4) and (5) were orally given Momordica charantia once a day at a dosage of 0.10, 0.20 and 0.40 mg/ml respectively, for 10 days. At the end of the experiment, blood samples from all mice were collected for a biochemical analysis. The results had an effect on the glucose level of the serum, at 0.30mg/ml of water extract of Momordica charantia. On the other hand, there are no effects on the glucose level at the higher dosages of Methanolic Momordica charantia extract.


Keywords: Momordica charantia,Glucose in Mice,Experimental diabetes.
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How to cite this article:

Maha Hameed A. Al-Bahrani. 2016. The Role of Momordica charantia in Reducing the Level of Glucose in Mice.Int.J.Curr.Microbiol.App.Sci. 5(8): 470-478. doi: http://dx.doi.org/10.20546/ijcmas.2016.508.050