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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(4): 2298-2306
DOI: https://doi.org/10.20546/ijcmas.2018.704.263


A Study of Microbial Colonization and their Antibiotic Resistance Pattern in Endotracheal Aspirate Cultures in Intensive Care Unit Patients at a Tertiary Care Hospital of Eastern UP
Vandana Upadhyay, Ankur Kumar*, Jayesh,  Amresh Kumar Singh
Department of Microbiology, BRD Medical College Gorakhpur, U.P., India
*Corresponding author
Abstract:

Nosocomial infections are a critical issue among intubated patients. Respiratory tract infection in relation to intubation and/ or mechanical ventilation has been reported to vary from 4% to 28% and this rate has been thought to be 21 times higher than in patients without endotracheal tube. The aim of our study was to identify the pathogens isolated from culture of endotracheal tube aspirates and determine their antibiogram. Patients on mechanical ventilation (MV) for >48 h in the intensive care units (ICU), critical care unit (CCU), PICU and NICU were included in this study. All the endotracheal aspirate samples were transported to the Microbiology laboratory for culture and sensitivity testing. In our study we observed a total of 101 ETAs culture positive isolates. The most common micro-organism was Klebseilla pneumoniae 28 (27%) and in Gram positive it was CONS 12 (12%). The highest resistance was found in 3rd generation cephalosporins and Penicillin group antibiotics, the least in carbapenems and polymyxin B. The key is early identification of the causative microbial agents, antibiotic sensitivity and administration of selected antibiotics. Our observations provide useful information regarding such respiratory infection. Thus ET tip cultures could be useful adjunct to the ATS strategy for ensuring appropriate treatment of intubated patients and in context of a bundled approach to the prevention of ET tip infections.


Keywords: Endotracheal tube, Ventilator-associated pneumonia, Nosocomial infection
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How to cite this article:

Vandana Upadhyay, Ankur Kumar, Jayesh, Amresh Kumar Singh. 2018. A Study of Microbial Colonization and their Antibiotic Resistance Pattern in Endotracheal Aspirate Cultures in Intensive Care Unit Patients at a Tertiary Care Hospital of Eastern UP.Int.J.Curr.Microbiol.App.Sci. 7(4): 2298-2306. doi: https://doi.org/10.20546/ijcmas.2018.704.263