National Academy of Agricultural Sciences (NAAS)
|
PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The presented work involved the preparation of compounds containing aromatic heterocyclic (thiazol ring) derived from substituted aminobenzoic acid. The first step involved the preparation of substituted esters of aminobenzoic acid (from 1 to 9 compounds) by reaction of substitutedaminobenzoic acid withthionyl chloride then with different alcohols such as (benzyl alcohol, allylalcohol, polyvinyl alcohol).The second step includes the reaction of the prepared compounds with chloroacetyl chloride in the presence of triethylamine to give compounds from (10 to 18). The third step involves the preparation of N-(2-amio thiazole) substituted aminobenzoatefrom the refluxe of cmpounds(10 to 18) with thiourea and DMF. All the prepared compounds in this work were characterized by melting point and softening points with other physical properties, FTIR, H1-NMR spectra.screening of the antimicrobial activity of the prepared thiazol compounds was evaluated against 2 types of bacteria.
Citations |
 |
 |
 |
 |
