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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(8): 1-13
DOI: http://dx.doi.org/10.20546/ijcmas.2016.508.001


Synthesis and Characterization of New Compounds containing 2-amino Thiazole Ring from Amino Benzoic Acid
Entesar O. Al-Tamimi* and Hussein F. Abdul Mahdi
University of Baghdad, college of science, Chemistry department, Baghdad, Iraq
*Corresponding author
Abstract:

The presented work involved the preparation of compounds containing aromatic heterocyclic (thiazol ring) derived from substituted aminobenzoic acid. The first step involved the preparation of substituted esters of aminobenzoic acid (from 1 to 9 compounds) by reaction of substitutedaminobenzoic acid withthionyl chloride then with different alcohols such as (benzyl alcohol, allylalcohol, polyvinyl alcohol).The second step includes the reaction of the prepared compounds with chloroacetyl chloride  in the presence of triethylamine to give compounds from (10 to 18). The third step involves the preparation of N-(2-amio thiazole) substituted aminobenzoatefrom the refluxe of cmpounds(10 to 18) with thiourea and DMF. All the prepared compounds in this work were characterized by melting point and softening points with other physical properties, FTIR, H1-NMR spectra.screening of the antimicrobial activity of the prepared thiazol compounds was evaluated against 2 types of bacteria.


Keywords: Aminobenzoic acid,substituted aminobenzoate, hetrocyclic,thiazol ring
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How to cite this article:

Entesar O. Al-Tamimi and Hussein F. Abdul Mahdi. 2016. Synthesis and Characterization of New Compounds containing 2-amino Thiazole Ring from Amino Benzoic Acid.Int.J.Curr.Microbiol.App.Sci. 5(8): 1-13. doi: http://dx.doi.org/10.20546/ijcmas.2016.508.001