Follow
International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2019) [Effective from January 1, 2019]For more details click here

Login as a Reviewer

Indexed in



National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

See Guidelines to Authors
Current Issues

Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(4): 946-953
DOI: https://doi.org/10.20546/ijcmas.2018.704.100


Prevalence of ESBL and MBL Producing Pseudomonas aeruginosa in a Tertiary Care Hospital in Tirunelveli
J.K. Jeyabharathi1 and I. Rejitha2
1Thoothukudi Government medical college hospital, Tamil Nadu, India
2Tirunelveli Government medical college hospital, Tamil Nadu, India
*Corresponding author
Abstract:

The present study was done to detect Extended spectrum β lactamase and metallo-β-lactamase producing isolates of Pseudomonas aeruginosa from various clinical samples from patients admitted in Tirunelveli Government medical college hospital. In this study we studied the prevalence of ESBL and MBL among 112 Pseudomonas aeruginosa isolates, following standard methods of isolation and identification of these bacteria from clinical materials. Out of 112 isolates of Pseudomonas aeruginosa, 32 were producing extended spectrum β lactamase enzyme producing isolates, 11 isolates were resistance to Imipenem. Of the 11 imipinem resistant isolates, 7 were metallo-β-Lactamase enzyme producing isolates. The present study underlines the unique problem that the presence of ESBL has led to the widespread use of Imipenem which in turn led to the emergence of MBLs. Infection caused by MBL (metallo-β-lactamase) positive isolates of Pseudomonas aeruginosa is important to identify because it poses not only therapeutic problem due to broad spectrum drug resistance, but also a serious concern for infection control.


Keywords: Pseudomonas aeruginosa, ESBL, MBL, Combined disc test
Download this article as Download

How to cite this article:

Jeyabharathi, J.K. and Rejitha, I. 2018. Prevalence of ESBL and MBL Producing Pseudomonas aeruginosa in a Tertiary Care Hospital in TirunelveliInt.J.Curr.Microbiol.App.Sci. 7(4): 946-953. doi: https://doi.org/10.20546/ijcmas.2018.704.100