National Academy of Agricultural Sciences (NAAS)
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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706 Issues : 12 per year Publisher : Excellent Publishers Email : editorijcmas@gmail.com / submit@ijcmas.com Editor-in-chief: Dr.M.Prakash Index Copernicus ICV 2018: 95.39 NAAS RATING 2020: 5.38 |
The present study was done to detect Extended spectrum β lactamase and metallo-β-lactamase producing isolates of Pseudomonas aeruginosa from various clinical samples from patients admitted in Tirunelveli Government medical college hospital. In this study we studied the prevalence of ESBL and MBL among 112 Pseudomonas aeruginosa isolates, following standard methods of isolation and identification of these bacteria from clinical materials. Out of 112 isolates of Pseudomonas aeruginosa, 32 were producing extended spectrum β lactamase enzyme producing isolates, 11 isolates were resistance to Imipenem. Of the 11 imipinem resistant isolates, 7 were metallo-β-Lactamase enzyme producing isolates. The present study underlines the unique problem that the presence of ESBL has led to the widespread use of Imipenem which in turn led to the emergence of MBLs. Infection caused by MBL (metallo-β-lactamase) positive isolates of Pseudomonas aeruginosa is important to identify because it poses not only therapeutic problem due to broad spectrum drug resistance, but also a serious concern for infection control.
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