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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(3): 1985-2000
DOI: https://doi.org/10.20546/ijcmas.2018.703.234


Study of Chlamydia trachomatis Infection in Infertile Females at a Tertiary Care Hospital in Mumbai, India
K.M. Lohi1*, C.A. Kumar1, M.N. Fonseca2, S.M. Baveja1 and Sagar S. Panchal3
1Department of Microbiology, L.T.M. Medical College, Mumbai, India
2Department of Obstetrics and Gynecology, L.T.M. Medical College, Mumbai, India
3Government Medical College, Nagpur, India
*Corresponding author
Abstract:

C.trachomatis is one of the most frequently detected sexually transmitted bacterial pathogen as per CDC. Chlamydial infection has major clinical and epidemiological significance in women. This study aims to determine the magnitude of C. trachomatis infection in infertile women and study associated sociodemographic factors. Prospective cross-sectional hospital based study. The study was approved by Institutional Ethics Committee. Two endocervical specimen were collected aseptically by per-speculum examination from 120 women aged 18-45 years. Of these, 90 patients presenting with infertility (primary or secondary) were taken as study group and 30 healthy term pregnant women of similar age group as control. Rapid antigen detection test and Grams stain were done using one swab for each test. C. trachomatis infection was seen in 2.2% (2/90) patients in primary infertility cases having infertility greater than 10 years. The mean age of all patients was 27 ± 3.6 years. The mean duration of infertility was 3.9 ± 1.8 years. They significantly belonged to lower socioeconomic group and had lower level of education. They presented predominantly with lower abdominal pain, vaginal discharge, polymenorrhea and dyspareunia. Tubal occlusion was significantly observed in the patients tested positive. A low prevalence of C. trachomatis infection was found in women presenting with primary infertility. Early screening by Chlamydia rapid antigen detection test and health education would help in early diagnosis and hence prevent complications. Further studies with a larger sample size are suggested.


Keywords: Antigen detection, Infertility, Tubal occlusion, Rapid test
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How to cite this article:

Lohi, K.M., C.A. Kumar, M.N. Fonseca, S.M. Baveja and Sagar S. Panchal. 2018. Study of Chlamydia trachomatis Infection in Infertile Females at a Tertiary Care Hospital in Mumbai.Int.J.Curr.Microbiol.App.Sci. 7(3): 1985-2000. doi: https://doi.org/10.20546/ijcmas.2018.703.234