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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(7): 586-591
DOI: http://dx.doi.org/10.20546/ijcmas.2016.507.065


Demonstration and Comparison of Keratin Pearl and Individual Cell Keratin in Oral Squamous Cell Carcinoma using Modified Mallory’s Stain and Hematoxylin and Eosin
Santhosh Kumar Caliaperoumal1*, R. Vezhavendhan2, A.Santha devy2, Priyavendhan2 and Uma devi2
1Department of Dentistry,Vinayaka Mission’s Medical college and Hospital,
Karaikal, Puducherry, India
2Department of Oral Pathology, Indira Gandhi Dental College & Hospital, Puducherry, India
*Corresponding author
Abstract:

Observation of Keratin pearl (KP) and individual cell keratin (ICK) is a major criteria in histopathological grading of oral squamous cell carcinoma (SCC). The aim of the study was to evaluate and compare the distinct staining and identification of KP and ICK by routine Hematoxylin & Eosin (H&E) stain and modified Mallory’s stain. The known cases of oral SCC with sufficient paraffin embedded tissue were selected. The two sections from each block were stained with H&E stain and modified Mallory’s stain. The modified Mallory’s stain distinctively and clearly stained KP and ICK compared to H&E stain. The positive staining of KP and ICK by modified Mallory’s stain was statistically significant with P=0.001, f=0.001 and P=0.022, f=0.034 than H&E stain. Based on our observation we conclude that the positive staining of KP and ICK in oral SCC by modified Mallory’s stain is statistically significant than H&E stain. So, modified Mallory’s stain can be used as an adjuvant stain along with H&E stain in case of oral SCC.


Keywords: Squamous cell carcinoma (SCC), Keratin Pearl(KP), Individual cell Keratin (ICK),modified Mallory’s stain, Hematoxylin and Eosin (H&E) stain.
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How to cite this article:

Santhosh Kumar Caliaperoumal, R. Vezhavendhan, A. Santha devy, Priyavendhan and Uma devi. 2016. Demonstration and Comparison of Keratin Pearl and Individual Cell Keratin in Oral Squamous Cell Carcinoma using Modified Mallory’s Stain and Hematoxylin and Eosin.Int.J.Curr.Microbiol.App.Sci. 5(7): 586-591. doi: http://dx.doi.org/10.20546/ijcmas.2016.507.065