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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(2): 3707-3715
DOI: https://doi.org/10.20546/ijcmas.2018.702.440


Fucoidan and Fucoidanase from Brown Seaweeds and Applications
Hamed M. El-Shora*, G. S. Abou-El-Wafa and N. M. Abu-Eftouh
Botany Department, Faculty of Science, Mansoura University, Egypt
*Corresponding author
Abstract:

Fucoidan is a biologically active polysaccharide found in brown seaweeds. The present study was carried out to isolate and investigate the biological activities of fucoidan and the activity of fucoidanase (EC: 3.2.1.44) from Padina pavonica, Sargassum latifolium and Colpomenia sinuosa. C. sinuosa expressed the highest fucoidan content and the highest fucoidanase activity. The isolated fucoidan from C. sinuosa expressed appreciable anticoagulant and antibacterial activities against Bacillus sp, Pseudomonas aeruginosa, Echerichia coli, Staphyllococcus aureus and Proteus vulgaris. It also showed antioxidant activity using DPPH [DPPH (1,1-diphenyl-2-picrylhydrazyl)] and ABTS [2, 2-azinobis (3-ethylbenzothiazoline- 6-sulfonic acid)] methods. Fucoidan from C. sinuos inhibited both α-glucosidase (EC: 3.2.1.20) and α-amylase (EC: 3.2.1.1). The inhibition of fucoidan for α-glucosidase activity was stronger than that of α-amylase activity. The results suggest that fucoidan from C. sinuosa can be used as antibacterial, antioxidant and antidiabetic.


Keywords: Fucoidan and Fucoidanase, brown seaweeds
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How to cite this article:

Hamed M. El-Shora, G. S. Abou-El-Wafa and Abu-Eftouh N. M. 2018. Fucoidan and Fucoidanase from Brown Seaweeds and Applications.Int.J.Curr.Microbiol.App.Sci. 7(2): 3707-3715. doi: https://doi.org/10.20546/ijcmas.2018.702.440