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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2018.7(2): 2489-2493
DOI: https://doi.org/10.20546/ijcmas.2018.702.303


Prevalence of Hepatitis C Virus Infection among Chronic Liver Disease Patients in a Tertiary Care Hospital
B.N. Vilas1, P.R. Lyra2* and D. Venkatesha3
1Sanjay Gandhi Institute of Trauma and Orthopaedics, Bangalore, Karnataka, India
2Department of Microbiology, East Point College of Medical Sciences and Research Centre, Bangalore, Karnataka, India
3Department of Microbiology, Adichunchanagiri Institute of Medical Sciences, Bellur, Karnataka, India
*Corresponding author
Abstract:

Hepatitis C virus (HCV) infection is a leading cause of chronic hepatitis and primary hepatocellular carcinoma in most parts of the world. The prevalence of HCV infection worldwide has been estimated to be about 3%. Hence the present study was carried out to detect the prevalence of hepatitis C in patients of chronic liver disease. Eighty patients with clinically suspected Chronic Liver Disease attending the outpatient department or admitted in the K R Hospital attached to Mysore Medical College and Research Institute, Mysore from January 2012 to December 2012, were screened for anti-HCV. The study also included 15 asymptomatic healthy individuals who constituted the control group. 5 ml of blood was collected from all patients with aseptic precautions, serum sample obtained were tested for serological marker anti-HCV using Erba Lisa Hepatitis C - third generation ELISA kits. Serum samples from healthy individuals included were also simultaneously screened for anti-HCV. Among the 80 chronic liver disease patients, 4(5%) were positive for HCV. Among the 4 HCV positive patients, all were males. The highest percentage of HCV positivity was in the age group 31 – 40 years. The main mode of transmission in HCV was through sexual exposure, 3 (75%). Among the 4 HCV positive patients, 3 (75%) presented with cirrhosis of liver and 1 (25%) with hepatocellular carcinoma. Among the healthy controls screened all were negative for anti HCV.


Keywords: HCV, Chronic liver disease
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How to cite this article:

Vilas, B.N., P.R. Lyra and Venkatesha, D. 2018. Prevalence of Hepatitis C Virus Infection among Chronic Liver Disease Patients in a Tertiary Care Hospital.Int.J.Curr.Microbiol.App.Sci. 7(2): 2489-2493. doi: https://doi.org/10.20546/ijcmas.2018.702.303