International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 5, Issue:6, June, 2016

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(6): 856-874

The Use of Some Traditional Herbs to Activating the Immunity of Diabetic Rats
Magbolah, S.H. Al-Zahrany*
 Biology Department, Faculty of Science, Al-baha University, KSA
*Corresponding author

The aim of this investigation is to evaluate the biological effect of herbs on lowering the level of glucose in blood and enhancement of the immune system. Thirty-two male albino rats (130 – 200 g) each were used in the study, 28 of rats diabetes by single intraperitoneal injection of alloxan at dose level of 150 mg / kg body weight. All rats (normal and diabetic) were kept on casein basal diet for 4 weeks. They were then divided into 5 groups. At the end of experiment the weight gain was calculated. Organs (liver–heart–kidney–spleen–lungs) of each rat were removed rapidly and were weighted separately. Blood samples were used for estimation of fasting serum glucose, serum GPT and GOT, serum lipid profile, kidney function, cellular and humoral immunity. Data showed that serum GOT and GPT levels declined significantly (p<0.01) in all treated groups that fed on 20% powder and extract when compared with diabetic control positive, while feeding rat on basal diet containing 20% herbs (2) extract, herbs (1) powder revealed more hypoglycemic effect. The best results for immunity were 20% herbs (3) powder, herbs (2) extract, herbs (2) powder group.

Keywords: Immunity,Liver enzymes, internal organs, rats,Diabetes mellitus, lipid profile

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How to cite this article:

Magbolah, S.H. Al-Zahrany. 2016. The Use of Some Traditional Herbs to Activating the Immunity of Diabetic Rats.Int.J.Curr.Microbiol.App.Sci. 5(6): 856-874. doi:
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.