International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 5, Issue:6, June, 2016

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(6): 742-752

UV and Solar Degradation of Ofloxacin Antibiotic
Gayatri Devi Singh, K.C. Gupta1* and Archana Shrivastawa2
1Department of Microbiology, VRG Girls College, Morar Gwalior, (M.P.) India
2Department of Microbiology, College of Life Science, Cancer Hospital and Research Institute Gwalior, (M.P.) India
*Corresponding author

The ofloxacin is a synthetic antibiotic, which belongs to the second generation of fluoroquinolones group. It acts against the Gram positive and Gram negative bacteria by inhibiting the DNA gyrase activity. The different concentrations of antibiotic solution ranging from 50 to 500 ppm, was exposed to the sun light and UV radiation. The solar exposure duration for the degradation, was 12 to 108 hrs. and UV exposure duration for the degradation, was 1 to 7 hrs. For the present study the UV radiation (15W and 30W) tubes, which were attached in the Laminar air flow, were used. The degradation capacity was measured by the zone of inhibition appeared after treatment. The maximum degradation of ofloxacin was recorded after 6 hrs. of exposure of UV (30W).  The higher solar degradation was also recorded at 108 hrs. exposure duration, but degradation efficiency was lower than UV exposure. For the control of pollution in the environment caused by ofloxacin antibiotic residues, was significantly controlled by the treatment of UV and the photolysis.

Keywords: Photodegradation, photolysis, ofloxacin, UV radiations, fluoroquinolones.

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How to cite this article:

Gayatri Devi Singh, K.C. Gupta and Archana Shrivastawa. 2016. UV and Solar Degradation of Ofloxacin Antibiotic.Int.J.Curr.Microbiol.App.Sci. 5(6): 742-752. doi:
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.