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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(6): 577-587
DOI: http://dx.doi.org/10.20546/ijcmas.2016.506.062


Bacterial Etiology: Significant In Allergic Respiratory Diseases
Kishori S. Tarfe1* and Sunita D. Deshpande2
1Department of Biotechnology, Smt CHM College, Ulhasnagar, Dist Thane, Maharashtra, India
2Former Professor, T. N. Medical College & B. Y. L. Nair charitable hospital, Mumbai, Maharashtra, India
*Corresponding author
Abstract:

Amongst allergic respiratory diseases allergic rhinitis & asthma are the most common. Asthma is a chronic inflammatory disease of the airways which in susceptible individuals causes recurrent episodes of wheezing, breathlessness, chest tightness & cough. Inflammation can cause increased airway hyperresponsiveness which can lead to infections by bacteria including atypical bacteria, fungi & viruses. Microbial infections associated with allergic respiratory infections increase severity & duration of the disease as well as they themselves act as an allergen. Therefore their treatment with appropriate antimicrobials is essential. Total 300 patients suffering from Asthma which is most common allergic respiratory disease were investigated for detection of bacterial pathogens in their sputum samples. Bacterial pathogens were isolated in 20% cases, which were M. catarrhalis, S. aureus, S. pyogenes, K. pneumoniae, & P. aeruginosa. M. catarrhalis was the most common isolate found in 19% cases followed by S. aureus in 28.33 % cases, K.pneumoniae & P. aeruginosa in 16.66 % cases each & S. pyogenes in 6.6 % cases. Antibiotic sensitivity testing was performed to determine their sensitivity pattern & it was observed that M. catarrhalis & S. pyogenes were sensitive to all the antibiotics tested. Other isolates showed variable susceptibility pattern. These isolates showed susceptibility to Aminoglycosides & cephalosporin group. Various bacteria play a major role in severity of exacerbations, symptoms & overall progress of allergic respiratory disease such as asthma. These bacterial infections can be diagnosed & treated with appropriate & specific antibiotics. This antibiotic treatment will help in fast recovery of patients with reduced duration of corticosteroid consumption of patients. 


Keywords: Asthma, Allergen, Airway hyper-responsiveness, inflammation.
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How to cite this article:

Kishori S. Tarfe and Sunita D. Deshpande. 2016. Bacterial Etiology: Significant In Allergic Respiratory Diseases.Int.J.Curr.Microbiol.App.Sci. 5(6): 577-587. doi: http://dx.doi.org/10.20546/ijcmas.2016.506.062