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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(12): 2669-2675
DOI: https://doi.org/10.20546/ijcmas.2017.612.308


Correlation of Glycated Hemoglobin and Iron Deficiency Anemia among Diabetic and Non Diabetic Patients
Vydehi Veeramalla1 and Swetha Madas2*
1Consultant Biochemist, Anupama Hospital, KPHB colony, Kukutpalli,Hyderabad, Telangana, India
2Department of TB and Chest, RVM Institute of Medical Sciences and Research Centre, Hyderabad, Telangana, India
*Corresponding author
Abstract:

Hemoglobin A1c (HbA1c), also known as glycated hemoglobin can be used as an indicator of a patient’s glycemic status for over a previous 3 months. Iron deficiency anemia (IDA) is one of the most prevalent forms of malnutrition. Reduced iron stores are shown to have a direct link with increased glycation of hemoglobin A1C (HbA1c), thereby leading to false-high values of HbA1c in the non-diabetic individuals. 98 diabetic patients and 86 non diabetic patients with anemia were included into the study. Hemoglobin levels, mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MHCH), mean corpuscular volume (MCV), hematocrit, platelet count, total blood picture, differential leucocyte count was done for all samples. Samples from patients were tested for serum ferritin and haemoglobin at base line, 1 month and 2 months following iron treatment. Out of the total 98 diabetic patients, 42.9% were males and 57% were females. Among the non-diabetes also, the predominant gender were females 58.1% and males were 41.9%. The most common type of anemia among the diabetic patients was severe, seen in 66.3% cases, followed by moderate in 31.6. At baseline the hemoglobin in the anemic patients was 6.3 g/dL, while the serum ferritin was 7.3 mg/ml and HbA1c was 6.2% and 12.1 g/dL, 259 mg/ml and 5.1% respectively after 2 months of treatment with iron supplements. The HbA1c levels showed considerable reduction after the treatment. Thus, whenever HbA1c is calculated to detect the glycemic status of a patient, factors other than glucose also play a part in its calculated value, which should be kept in mind before a therapeutic treatment is given.


Keywords: Glycated hemoglobin, Iron deficiency anemia, Diabetic patients, Non-diabetic patients.
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How to cite this article:

Vydehi Veeramalla and Swetha Madas. 2017. Correlation of Glycated Hemoglobin and Iron Deficiency Anemia among Diabetic and Non Diabetic Patients.Int.J.Curr.Microbiol.App.Sci. 6(12): 2669-2675. doi: https://doi.org/10.20546/ijcmas.2017.612.308