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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(12): 1925-1928
DOI: https://doi.org/10.20546/ijcmas.2017.612.219


Seroprevalence of Rheumatoid Factor in Arthritis Cases in a Teritiary Care Hospital
S. Chandrasekhar1 and Ramalakshmi Koripella2*
1Department of Orthopaedics
2Department of Microbiology,Andhra Medical College, Visakhapatnam, AP, India
*Corresponding author
Abstract:

Rheumatoid arthritis is a chronic, severe, progressive inflammatory autoimmune disease of uncertain etiology involving multiple peripheral joints. Rheumatoid arthritis is diagnosed according to clinical findings and serological testing. The main useful serological markers are rheumatoid factor and antibodies to citrullinated peptides. The present study was done to know the prevalence of Rheumatoid factor as a serological marker in clinically suspected arthritis cases in a tertiary care hospital. 100 blood samples from orthopaedic department received in the microbiology department were tested for RF out of 100 patients 68 were females and 32 males. Most of the patients were between the age group 20 – 50 years. The prevalence of RF was 7%. Out of 7 RF positive cases 5 were females and 2 were males. Rheumatoid factor alone may be of little value as a screening test to diagnose or exclude rheumatic disease in either healthy populations or those with arthralgias. For evaluation of patients with suspected rheumatoid arthritis it is recommended to perform cyclic citrullinated peptide antibody and IgM rheumatoid factor to increase both the sensitivity and specificity of the results.


Keywords: Rheumatoid arthritis, Serological markers, Rheumatoid factor, IgM antibody, Citrullinated peptide antibody.
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How to cite this article:

Chandrasekhar, S. and Ramalakshmi Koripella. 2017. Seroprevalence of Rheumatoid Factor in Arthritis Cases in a Teritiary Care Hospital.Int.J.Curr.Microbiol.App.Sci. 6(12): 1925-1928. doi: https://doi.org/10.20546/ijcmas.2017.612.219