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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(6): 150-160
DOI: http://dx.doi.org/10.20546/ijcmas.2016.506.019


Its Alarming, Klebsiella spp. towards Multidrug Resistance
Manish Pokra*, Dileep Kumar Sharma, Pushpa Mehta, Harsha Rani Verma, Smariti Pundir, Jyoti Rana and  Durgalal Kulmi
Department of Microbiology, Jhalawar medical college, Jhalawar, India
*Corresponding author
Abstract:

Klebsiella pneumoniae and Klebsiella oxytoca  are the two most frequently encountered Klebsiella species giving rise to infections in humans. Klebsiella spp. causes urinary tract infections, ventilator-acquired pneumonias and blood stream infections (sepsis) among other conditions and is proving to be fatal. Klebsiella spp. has been associated with various types of infections and recently one of the most important and alarming aspects of Klebsiella spp. is the emergence of multi-drug resistant strains particularly those involved in nosocomial infection. Bacteria producing Klebsiella carbapenemases and extended-spectrum β-lactamases(ESBL), are rapidly emerging as a cause of multidrug-resistant infections worldwide. Bacterial isolates harbouring these enzymes are capable of hydrolysing a broad spectrum of β-lactams including the penicillins, cephalosporins, carbapenems and monobactam. Several cases which are almost resistant to all the antibiotic compel us to study its pattern. About hundred clinical isolates were collected from different wards, Icu, Nicu, Picu, postoperative wards of Tertiary care hospital of Jhalawar district. Out of which fifty two confirmed sample of Klebsiella spp.were  further tested for antimicrobial drug susceptibility. The study is done in period of seven month from sep.2015 to march 2016.


Keywords: Klebsiella pneumoniae, multi-drug resistant strains, β-lactams.
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How to cite this article:

Manish Pokra, Dileep Kumar Sharma, Pushpa Mehta, Harsha Rani Verma, Smariti Pundir, Jyoti Rana and  Durgalal Kulmi. 2016. Its Alarming, Klebsiella spp. towards Multidrug Resistance.Int.J.Curr.Microbiol.App.Sci. 5(6): 150-160. doi: http://dx.doi.org/10.20546/ijcmas.2016.506.019