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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2017: 100.00
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2017: 100.00
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(11): 2610-2616
DOI: https://doi.org/10.20546/ijcmas.2017.611.306


Prevalence of Candida Species with their Antifungal Susceptibility Pattern from Blood and Urine Cultures in Gauhati Medical College Hospital, Guwahati, India
Nabajit Deka* and N.K. Hazarika
Department of Microbiology, Gauhati Medical College Hospital, Guwahati-781032, Assam, India
*Corresponding author
Abstract:

Although yeast cells are often present as benign commensal organisms of healthy individuals, specially Candida has become emerge pathogen in last few decades due to various factors like AIDS and increased number of patients receiving immunocompromised drugs during organ transplantation and cancer therapy. Along with rise of incidence of candida infection, the emergence of drug resistance further worsens the situation. So we have studied the prevalence of candida species from blood and urine sample. Out of total 167 samples, C. albicans were identified as 44 (26.3%) and remaining 123 (73.65%) were Non Albican Candida (NAC). Among Non Albican Candida (NAC), C. krusei was major isolate i.e.48 (28.7%) followed by C. tropicalis (14.9%) and other non-albicans Candida species. In our study about the susceptibility pattern of candida species to Amphotericine B, Fluconazole, Itraconazole, Voriconaole, Ketoconazole, Nystatin we have found that C. albicans was found resistant to Fluconazole, Ketoconazole in 22.7% and 13.6% cases respectively. For NAC, resistance to Fluconazole was found maximum in C. krusei 20 (41.6%) out of 48 isolates followed by C. parapsilosis 3 (13%) and C. tropicalis 3 (12%) out of 23 and 25 isolates respectively. No resistance was detected against Amphotericine B, Voriconazole, Nystatin and Itraconzole except C. tropicalis which is 2 (8%) out of 25 isolates against Itraconazole. On the other hand all C. glabrata isolates were sensitive to all antifungals.


Keywords: Candida species, Candia albicans, NAC, Antifungal, Disc Diffusion Method, MIC strip Test, CROM Agar, Sugar assimilation, Vitek card.
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How to cite this article:

Nabajit Deka and Hazarika, N.K. 2017. Prevalence of Candida Species with their Antifungal Susceptibility Pattern from Blood and Urine Cultures in Gauhati Medical College Hospital, Guwahati.Int.J.Curr.Microbiol.App.Sci. 6(11): 2610-2616. doi: https://doi.org/10.20546/ijcmas.2017.611.306