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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2016.5(6): 1-15
DOI: http://dx.doi.org/10.20546/ijcmas.2016.506.001


Healthcare Associated Infections and Patterns of Antibiotic Resistance in Tropical Medicine Department in Egypt
Heba Eldegla1,2, Waleed Eldars1,2, Maggie R. Mesbah1,2*, Raghda El-Sayed Farag3,Nasser Mousa3, Mahmoud Abdel-Aziz3 and Ahmed Abd Elrazik3
1Medical Microbiology and Immunology Department, Faculty of Medicine,
Mansoura University, Egypt
2Microbiology Diagnostics and Infection Control Unit, Mansoura University Hospitals, Egypt
3Tropical Medicine Department, Faculty of Medicine, Mansoura University, Egypt
*Corresponding author
Abstract:

Health-care-associated infection (HAI) is a major problem in hospitals worldwide. This study was conducted to describe culture-confirmed HAIs, its patterns of antibiotic resistance and risk factors for acquiring HAIs and multidrug resistant (MDR) pathogens. A retrospective analysis was made between January 2013 and August 2015 for HAIs among7063 patients in tropical medicine department in Mansoura University Hospital, Egypt. A total of 1658 samples were collected for culture, isolation, identification and antibiotic susceptibility of nosocomial pathogens. Multidrug resistant pathogens were characterized phenotypically and extended spectrum β lactamase (ESBL) production was assessed by modified double disc synergy test(MDDS). HAI rate was 2.4/100 admission and 5.07/1000 patient days. The most common site of infection was urinary tract infection (UTI) (45.2%) and the most frequent nosocomial pathogen was E.coli (27.9%). Multi drug resistant organisms (MDRO) accounted for 40.6% of all bacterial isolates. The highest prevalence of ESBL production was among E.coli (47.6%). Age >65 years; invasive device utilization; neutropenia, abdominal paracentes is and hospital stay longer than seven days were significantly associated with HAI occurrence. Multiple antibiotic therapy, use of beta lactam, invasive device utilization and hospital stay longer than seven days were significantly associated with MDRO acquisition. The cumulative incidence of HAI in this study was low; however, the high rates of UTI and multi-resistant pathogens necessitate urgent comprehensive interventions of infection control.


Keywords:

HAI,Multidrug resistant organisms,UTI.modified double disc synergy test(MDDS)

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How to cite this article:

Heba Eldegla, Waleed Eldars, Maggie R. Mesbah, Raghda El-Sayed Farag, Nasser Mousa,  Mahmoud Abdel-Aziz and Ahmed Abd Elrazik. 2016. Healthcare Associated Infections and Patterns of Antibiotic Resistance in Tropical Medicine Department in Egypt.Int.J.Curr.Microbiol.App.Sci. 5(6): 1-15. doi: http://dx.doi.org/10.20546/ijcmas.2016.506.001