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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(10): 4830-4837
DOI: https://doi.org/10.20546/ijcmas.2017.610.451


Antibiogram of Urinary Pathogens in Patients with Diabetes Mellitus - Experience from a Tertiary Care Hospital
B.K. Rashmi* and D.T. Venkatesha
Department of Microbiology, Hassan Institute of Medical Sciences, Hassan 573201, Karnataka, India
*Corresponding author
Abstract:

Urinary Tract Infections (UTIs) in diabetics tends to remain a major health hazard, which are responsible for significant morbidity. It is Cross-sectional study. The urine samples were processed according to the standard protocol over a period of one year from March 2015 to May 2016. The antimicrobial susceptibility was tested by the modified Kirby-Bauer’s disc diffusion method as per the CLSI guidelines. Out of 400 diabetic patients, 185 (46.5%) had symptoms of UTI. Culture positivity was observed in 80.54% (149/185). Most common age group affected was between 46 -55 years (mean age is 53.8). Out of 149 culture positive samples, 112 (60.54%) Gram-negative bacilli and 37 (20%) Gram-positive cocci were isolated. The most common isolated uropathogen was E. coli (34.1%) followed by Klebsiella pneumoniae (15.1%), Enterococcus species (11.4%), Coagulase Negative Staphylococcus (cons) (1.6%), Staphylococcus aureus (7.02%), Acinetobacter species (3.2%), Citrobacter species (0.5%), Pseudomonas aeruginosa (5.9%), and Proteus species (1.6%). Among Gram negative bacilli, Imipenem (94.64%), Tobramycin (87.5%), Pipercillin-Tazobactum (75%), Amikacin (74.7%), Gentamicin (63.39%), Amoxicillin-Clavulinic acid (61.6%), Ceftazidime-Clavulanic acid (58.03%), Ceftriaxone (25.8%), Norfloxacin (25.4%) were found to be the most effective drugs. Among Gram positive pathogens Linezolid (100%), Vancomycin (67.7%), Amikacin (54.05%), Amoxycillin-Clavulanic acid (52%) were found to be more sensitive.


Keywords: Urinary Tract Infection, Uropathogens, Antimicrobial sensitivity, Drug resistance.
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How to cite this article:

Rashmi, B.K. and Venkatesha, D.T. 2017. Antibiogram of Urinary Pathogens in Patients with Diabetes Mellitus - Experience from a Tertiary Care HospitalInt.J.Curr.Microbiol.App.Sci. 6(10): 4830-4837. doi: https://doi.org/10.20546/ijcmas.2017.610.451