Follow
International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020]For more details click here

Login as a Reviewer

Indexed in



National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2019: 96.39
Index Copernicus ICI Journals Master List 2019 - IJCMAS--ICV 2019: 96.39
For more details click here

See Guidelines to Authors
Current Issues

Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(10): 3488-3495
DOI: https://doi.org/10.20546/ijcmas.2017.610.411


In Vitro Evaluation of Natural Keratin Based Hydrogel from Chicken Feather Waste for Controlled Drug Release
D. Sakthi Chandini1, M. Charulatha2, R. Legadevi2 and S. Meignanalakshmi2*
1Madha Engineering College, Chennai-69, Tamil Nadu, India
2Department of Animal Biotechnology, Madras Veterinary College, TANUVAS,Chennai-7, Tamil Nadu, India
*Corresponding author
Abstract:

In the present study keratin was extracted from chicken feather using the reductants beta mercaptoethanol, urea and SDS. The extracted keratin was lyophilised and was used to prepare hydrogel. Prepared hydrogel was characterized using SEM and FTIR. The prepared keratin hydrogel was used for encapsulation of tetracycline. The percentage of drug encapsulation in keratin hydrogel was found to be 92.5%. The in vitro release of tetracycline from keratin hydrogel was carried out in PBS for 24hrs and was found to be released in a slow and sustained manner.


Keywords: Chicken Feathers, Keratin Hydrogel, Drug encapsulation.
Download this article as Download

How to cite this article:

Sakthi Chandini, D., M. Charulatha, R. Legadevi and Meignanalakshmi, S. 2017. In Vitro Evaluation of Natural Keratin Based Hydrogel from Chicken Feather Waste for Controlled Drug Release.Int.J.Curr.Microbiol.App.Sci. 6(10): 3488-3495. doi: https://doi.org/10.20546/ijcmas.2017.610.411