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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here
ICV 2022: 95.28
Index Copernicus ICI Journals Master List 2022 - IJCMAS--ICV 2022: 95.28
For more details click here
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Original Research Articles                      Volume : 6, Issue:10, October, 2017
PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com /
submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38
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Int.J.Curr.Microbiol.App.Sci.2017.6(10): 3488-3495
DOI: https://doi.org/10.20546/ijcmas.2017.610.411


In Vitro Evaluation of Natural Keratin Based Hydrogel from Chicken Feather Waste for Controlled Drug Release
D. Sakthi Chandini1, M. Charulatha2, R. Legadevi2 and S. Meignanalakshmi2*
1Madha Engineering College, Chennai-69, Tamil Nadu, India
2Department of Animal Biotechnology, Madras Veterinary College, TANUVAS,Chennai-7, Tamil Nadu, India
*Corresponding author
Abstract:

In the present study keratin was extracted from chicken feather using the reductants beta mercaptoethanol, urea and SDS. The extracted keratin was lyophilised and was used to prepare hydrogel. Prepared hydrogel was characterized using SEM and FTIR. The prepared keratin hydrogel was used for encapsulation of tetracycline. The percentage of drug encapsulation in keratin hydrogel was found to be 92.5%. The in vitro release of tetracycline from keratin hydrogel was carried out in PBS for 24hrs and was found to be released in a slow and sustained manner.


Keywords: Chicken Feathers, Keratin Hydrogel, Drug encapsulation.

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How to cite this article:

Sakthi Chandini, D., M. Charulatha, R. Legadevi and Meignanalakshmi, S. 2017. In Vitro Evaluation of Natural Keratin Based Hydrogel from Chicken Feather Waste for Controlled Drug Release.Int.J.Curr.Microbiol.App.Sci. 6(10): 3488-3495. doi: https://doi.org/10.20546/ijcmas.2017.610.411
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.

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