International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 6, Issue:10, October, 2017

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(10): 3488-3495

In Vitro Evaluation of Natural Keratin Based Hydrogel from Chicken Feather Waste for Controlled Drug Release
D. Sakthi Chandini1, M. Charulatha2, R. Legadevi2 and S. Meignanalakshmi2*
1Madha Engineering College, Chennai-69, Tamil Nadu, India
2Department of Animal Biotechnology, Madras Veterinary College, TANUVAS,Chennai-7, Tamil Nadu, India
*Corresponding author

In the present study keratin was extracted from chicken feather using the reductants beta mercaptoethanol, urea and SDS. The extracted keratin was lyophilised and was used to prepare hydrogel. Prepared hydrogel was characterized using SEM and FTIR. The prepared keratin hydrogel was used for encapsulation of tetracycline. The percentage of drug encapsulation in keratin hydrogel was found to be 92.5%. The in vitro release of tetracycline from keratin hydrogel was carried out in PBS for 24hrs and was found to be released in a slow and sustained manner.

Keywords: Chicken Feathers, Keratin Hydrogel, Drug encapsulation.

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How to cite this article:

Sakthi Chandini, D., M. Charulatha, R. Legadevi and Meignanalakshmi, S. 2017. In Vitro Evaluation of Natural Keratin Based Hydrogel from Chicken Feather Waste for Controlled Drug Release.Int.J.Curr.Microbiol.App.Sci. 6(10): 3488-3495. doi:
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.