International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 6, Issue:10, October, 2017

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(10): 2054-2058

Dengue NS1 Antigen for Early Detection of Dengue Infection
J.V. Sathish, Mita D. Wadekar* and C. Pooja
J.V. Sathish, Mita D. Wadekar* and C. Pooja
*Corresponding author

Dengue is a mosquito-borne viral disease affecting tropical and subtropical regions of the world. Symptoms may range from a mild undifferentiated febrile illness to dengue fever (DF) and dengue haemorrhagic fever (DHF), a potentially life threatening disease. Detection of non-structural antigen (NS1 Ag) may help in the early diagnosis and treatment of dengue. Aim of the study is to detect dengue infection by NS1 Ag detection and also to know its prevalence. A retrospective study was carried out in a tertiary-care hospital in Chamarajanagar, Karnataka, India. The serum samples from 787 suspected dengue cases which included patients of all age group and from both gender, were subjected to dengue NS1 antigen detection by microwell enzyme-linked immunosorbent assay (ELISA). Of 787 serum samples tested, 286 (36.34%) samples were positive for NS1 antigen. Maximum number of positive cases were in age groups of 0-18 years 70 (24.48%) followed by 19-45 years 69 (24.12%) with no significant difference between males 64 (54.70%) and females 53(45.30%). Prevalence of dengue 36.34% is high in our locality. So a prevention strategy has to be taken. NS1 Ag detection has a significant role in early diagnosis of dengue fever. Hence, it is recommended to do this test for early diagnosis and treatment.

Keywords: Dengue fever, NS1 antigen, Early detection.

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How to cite this article:

Sathish, J.V., Mita D. Wadekar and Pooja, C. 2017. Dengue NS1 Antigen for Early Detection of Dengue InfectionInt.J.Curr.Microbiol.App.Sci. 6(10): 2054-2058. doi:
Copyright: This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike license.