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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2018: 95.39
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(10): 145-150
DOI: https://doi.org/10.20546/ijcmas.2017.610.018


Thrombocytopenia – An Indicator of Impending Complications in Dengue Virus Infection
Kanthishree B. Haritsa1, S. Sangeetha1* and Mamatha B. Patil2
1Department of Microbiology, 2Department of General Medicine, Rajarajeswari Medical College and Hospital, Bangalore, Karnataka, India
*Corresponding author
Abstract:

Dengue virus infection is a major public health problem in urban, semi-urban and rural India. At times, the platelet count is the only accessory laboratory test available in the peripheral areas. Thrombocytopenia in clinically suspected patients of dengue infection can serve as a predictor of DHF or DSS and guide in the institution of early supportive and maintenance therapy. Hence in this study, correlation of platelet count with dengue parameters was done keeping in mind the constraints in the facilities in the peripheral health system. The study was conducted in a tertiary care teaching hospital. A total of 86 serum samples were subjected to NS1 ELISA and IgM ELISA. Platelet count of all the patients was noted. Chi square test was applied for analysis of categorical data. Out of 86 clinically suspected cases, 64 patients were positive for dengue parameters and remaining 22 patients were negative. There was good association between low platelet count and dengue positive parameters than with dengue negative parameters. (P value < 0.001) In clinically suspected cases of dengue infection, if thrombocytopenia is observed, early and prompt therapy should be instituted in order to reduce the morbidity and mortality due to complications of dengue infection.


Keywords: Thrombocytopenia, DHF, DSS, ELISA, Peripheral Health System.
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How to cite this article:

Kanthishree B. Haritsa, S. Sangeetha and Mamatha B. Patil. 2017. Thrombocytopenia – An Indicator of Impending Complications in Dengue Virus InfectionInt.J.Curr.Microbiol.App.Sci. 6(10): 145-150. doi: https://doi.org/10.20546/ijcmas.2017.610.018