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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(10): 72-86
DOI: https://doi.org/10.20546/ijcmas.2017.610.009


Evaluation of Protective Potential of Curcuma longa in Induced Aflatoxicosis in Broiler Birds
L. Raja1, Chandan Kumar Singh3, M. Mondal2, S. Nety1 and K. M. Koley1
1Department of Veterinary Pharmacology and Toxicology, College of Veterinary Science and A.H., CGKV, Durg, Chhattisgarh, India
2Department of Teaching Veterinary Clinical Complex, Faculty of Veterinary and Animal Sciences, West Bengal University of Animal and Fishery Sciences, Kolkata, India
3Department of Veterinary Surgery and Radiology, College of Veterinary Science, Khanapara, Assam Agricultural University, India
*Corresponding author
Abstract:

The present study was undertaken to evaluate the ameliorative effects of Curcuma longa rhizome powder (1%) in induced aflatoxicosis in broiler chicken. In this study, commercially available broiler chickens of Vencobb strain were reared from day one to forty two days in the deep litter system of management and the birds were divided into three groups. Normal feed tested free of aflatoxin (AF), was given to the control (Group-1). Aflatoxin (1 ppm) was supplemented with the feed to Group 2 and Curcuma longa (1%) + AF was supplemented with the feed to Group 3. Biochemical parameters like Total serum protein, Albumin, Globulin, Albumin / Globulin ratio, blood glucose, AST, ALT, uric acid and serum creatinine were estimated. The results showed that the supplementation of C. longa (1 %) + AF partially restored the biochemical alterations induced by the AF. At the sixth week of age, two birds from each replicate were sacrificed to evaluate the oxidative stress parameters (reduced glutathione levels, Lipid peroxidation, Catalase) in the liver and kidney. The results showed that the AF causes a marked oxidative stress in comparison to control, which was partially reversed by the supplementation of the C. longa (1%) in the feed. However, C. longa significantly improved the antioxidant status in induced aflatoxicosis and partially protected against the cytotoxic effects of AFB1 in broiler birds.


Keywords: Aflatoxicosis, Biochemical changes, Broilers, Curcuma longa, Oxidative stress.
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How to cite this article:

Raja, L., Chandan Kumar Singh, M. Mondal, S. Nety and Koley, K.M. 2017. Evaluation of Protective Potential of Curcuma longa in Induced Aflatoxicosis in Broiler Birds.Int.J.Curr.Microbiol.App.Sci. 6(10): 72-86. doi: https://doi.org/10.20546/ijcmas.2017.610.009