International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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Original Research Articles                      Volume : 6, Issue:9, September, 2017

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : /
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(9): 3710-3716

Antibiogram of Methicillin- Resistant Staphylococcus aureus Isolates among Healthy Human Subjects in Oleh, South-Southern Nigeria
C. O. Anie1, M. C. Ugwu2*, E. C. Ibezim3 and C. O. Esimone2
1Faculty of Pharmacy Delta state University, Abraka Delta State, Nigeria
2Department of Pharmaceutical Microbiology and Biotechnology, Nnamdi Azikiwe University, Awka, Anambra State, Nigeria
3Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka, Enugu State, Nigeria
*Corresponding author

Methicillin-resistant Staphylococcus aureus (MRSA) is one of the major causes of hospital-acquired infections worldwide. It is widespread in communities and prevalent in hospital and even amongst the livestock.The mortality and morbidity amongst patients with infections associated with MRSA are usually high owing to increasing resistance to several antibiotics. The resistant pattern of MRSA has not been clearly defined in Oleh. This study was designed to determine the incidence and antibiotics resistant pattern of MRSA from the healthy students in Oleh campus, south-southern Nigerian locality. Methods: Three hundred (300) specimens were collected and appropriate procedures were followed for identification and susceptibility testing. The MRSA was determined using Oxacillin antibiotic disc. Of the 300 nasal swab samples collected and screened, a total 164 (72.7%) of the isolates were found to be S. aureus based on morphology and biochemical tests. The incidence rate from female to male individuals were 78(57 %) and 87 (52 %) respectively. The incidence rate of MRSA and colonisation among healthy individuals in the community was 15.7% (47/300) and 28.7 % (47/164) of the S. aureus isolates. The antibiotic resistant pattern of MRSA isolates was ciprofloxacin ~ ofloxacin ~ amoxicillin clavulanate > gentamicin,> co-trimoxazole > chloramphenicol > erythromycin > streptomycin >amoxicillin Although, multi-drug resistant strains of S. aureus have been identified in this study, infections caused by S aureus infections could be treated with flouroquinolones and Gentamicin.

Keywords: MRSA, Resistance, antibiotics susceptibility, tertiary Students, Delta state

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Anie C. O., M. C. Ugwu, E. C. Ibezim and Esimone C. O. 2017. Antibiogram of Methicillin- Resistant Staphylococcus aureus Isolates among Healthy Human Subjects in Oleh, South-Southern NigeriaInt.J.Curr.Microbiol.App.Sci. 6(9): 3710-3716. doi:
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