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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(9): 75-80
DOI: https://doi.org/10.20546/ijcmas.2017.609.008


Phenotypic Characterization and Susceptibility Pattern of Gram Negative Bacterial Isolates from Cases of Central Line Associated Blood Stream Infections in a Tertiary Care Institute
Akhilesh, P.S. Tomar1*, Anjali Kushwah2 and Harshada Shah3
1Department of Microbiology, NSCB Medical College, Jabalpur (MP)-482003, India
2Department of Pharmacology, G R Medical College, Gwalior (MP), India
3Department of Microbiology, R D Gardi Medical College, Ujjain (MP), India
*Corresponding author
Abstract:

Resistant and specially Multi Drug Resistant (MDR) Gram negative isolates from the cases of Central Line Associated Blood Stream Infections (CLABSI) are a serious challenge for the treatment to clinicians. Present study was undertaken for phenotypic characterization and susceptibility pattern of Gram negative bacterial isolates from cases of CLABSI in a tertiary care institute. Materials this descriptive cross sectional hospital based study was conducted in a tertiary care teaching hospital over a period of one and half year from January 2012 to June 2013. Centers for Disease Control and Prevention (CDC™s) CLABSI case definitions were used to label a case as CLABSI. Only culture proven cases, out of clinically suspected was included in the study for evaluation. Incidence Central Line Associated Blood Stream Infections were (0.31%) with 38 culture positive cases. The overall rate of CLABSI was 14.64 per 1000 device days with (0.04) device utilization ratio. Gram negative isolates predominated (79%) over Gram positive isolates (21). Among Gram negative bacterial isolates from CLABSI, Klebsiella pneumoniae (40%) was the commonest followed by E. coli (26.66%). %). Rising trends of antimicrobial resistance for common Gram negative bacterial isolates were noticed. Continuous surveillance of CLABSI and microbiological reporting of culture isolates is a need of time in the health care facility.


Keywords: Central Line Associated Blood Stream Infections, Gram negative bacterial infection, Multi Drug Resistant.
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How to cite this article:

Akhilesh, P.S. Tomar, Anjali Kushwah and Harshada Shah. 2017. Phenotypic Characterization and Susceptibility Pattern of Gram Negative Bacterial Isolates from Cases of Central Line Associated Blood Stream Infections in a Tertiary Care Institute.Int.J.Curr.Microbiol.App.Sci. 6(9): 75-80. doi: https://doi.org/10.20546/ijcmas.2017.609.008