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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(9): 976-980
DOI: https://doi.org/10.20546/ijcmas.2017.609.118


Most Common Isolates in Neonatal Sepsis, a Prospective Study in Tertiary Care Hospital
Patta Apparao*, Jyoti Nagdev and P. Siddartha
1Department of Microbiology, Late Shri Lakhiram Agrawal Memorial Medical College, (C.G.), India
2Dr. C.V.R. University, Kota, Bilaspur (C.G.), India
3NRI, Medical College, Vishakhapatnam, India
*Corresponding author
Abstract:

Neonatal sepsis is one of the most common causes of mortality and morbidity, particularly the developing countries. Accurate and timely diagnosis of neonatal sepsis remains a major challenge to the pediatricians and neonatologists. The objective of this study was to determine the causative bacteria and pattern of susceptibility to antibiotics in NICU of a tertiary care center, which in turn may help in implementation of empirical therapy. This prospective study was carried out in the department of microbiology, Govt. medical college Raigarh (c.g.) during Jun 2016- Jun 2017. A total of 255 cases of blood cultures are donein our microbiology department. Out of which, 120 cases were positive (Bac Talert) for culture. A total of 120 cultures were found to be positive out of 255 cases (47.0%). The most common organism isolated was Staphylococcus aureus (40.2%), followed by Klebsiella pneumonia (37 %) and Escherichia coli (14%) other organisms were much less in number. which included pathogenic Streptococci, coagulase negative Staphylococcus (CoNS), Pseudomonas, Acinetobacter and Enterobacter species. Candida albicans also isolated. The gram positive organisms except Streptococci displayed a high degree of resistance to most penicillins and ciprofloxacin but were sensitive to vancomycin, amikacin and linezolid. There was a high incidence of resistance noted with ampicillin, gentamicin and ciprofloxacin, amongst most gram negative organisms’ where in ceforuxime, amikacin and meropenem, imipenem, netilmycin were effective in most cases. There is an increasing trend of antibiotic resistance to the commonly used first line drugs. Continuous surveillance for antibiotic susceptibility is needed to ensure proper empirical therapy.


Keywords: Neonates, Empirical therapy, Early onset sepsis, late onset sepsis, Antimicrobial sensitivity.
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How to cite this article:

Patta Apparao, Jyoti Nagdev and Siddartha, P. 2017. Most Common Isolates in Neonatal Sepsis, a Prospective Study in Tertiary Care Hospital.Int.J.Curr.Microbiol.App.Sci. 6(9): 976-980. doi: https://doi.org/10.20546/ijcmas.2017.609.118