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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
National Academy of Agricultural Sciences (NAAS) : NAAS Score: *5.38 (2020) [Effective from January 1, 2020]For more details click here

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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2020)
[Effective from January 1, 2020]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2018: 95.39
NAAS RATING 2020: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(9): 879-885
DOI: https://doi.org/10.20546/ijcmas.2017.609.106


Antioxidant and Anticancer Study of Boerhavia erecta
M. Ismail Shareef, S.M. Gopinath*, Ayushi Gupta and Sonia Gupta
Department of Biotechnology, Acharya Institute of Technology, Bangalore, Karnataka, India
*Corresponding author
Abstract:

Boerhavia erecta, an annual herb, has been used in folklore for managing of a wide range of diseases including cancer. However, the safety and effectiveness of this medicinal plant was better evaluated. The intention of this study was to evaluate the in-vitro antioxidant and anticancer activities of whole plant extract of Boerhavia erecta well as the qualitative phytochemical constituents. The DPPH and nitric oxide scavenging assays were used to evaluate the plant’s antioxidant potential. The in-vitro3-(4, 5- Dimethylthiazol-2-yl)-2, 5-Diphenyltetrazolium Bromide (MTT) assay was exploited for determination of in-vitro anticancer activity against two cell lines: Mouse fibroblastic cell lines (L929), it’s a normal cell line and human brain tumor cell lines (U87), it’s a cancer cell line. Ascorbic acid and quercetin were used a standard antioxidant compound. The IC50 and CTC50 values were also estimated for antioxidant and anticancer studies respectively.


Keywords: Boerhavia erecta, DPPH, Nitric oxide Scavenging activity, Cytotoxicity, MTT assay.
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How to cite this article:

Ismail Shareef, M., S.M. Gopinath, Ayushi Gupta and Sonia Gupta. 2017. Antioxidant and Anticancer Study of Boerhavia erecta.Int.J.Curr.Microbiol.App.Sci. 6(9): 879-885. doi: https://doi.org/10.20546/ijcmas.2017.609.106