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International Journal of Current Microbiology and Applied Sciences (IJCMAS)
IJCMAS is now DOI (CrossRef) registered Research Journal. The DOIs are assigned to all published IJCMAS Articles.
Index Copernicus ICI Journals Master List 2018 - IJCMAS--ICV 2018: 95.39 For more details click here
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National Academy of Agricultural Sciences (NAAS)
NAAS Score: *5.38 (2019)
[Effective from January 1, 2019]
For more details click here

ICV 2018: 95.39
Index Copernicus ICI Journals Master List 2017 - IJCMAS--ICV 2018: 95.39
For more details click here

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Original Research Articles

PRINT ISSN : 2319-7692
Online ISSN : 2319-7706
Issues : 12 per year
Publisher : Excellent Publishers
Email : editorijcmas@gmail.com / submit@ijcmas.com
Editor-in-chief: Dr.M.Prakash
Index Copernicus ICV 2017: 100.00
NAAS RATING 2018: 5.38

Int.J.Curr.Microbiol.App.Sci.2017.6(8): 783-788
DOI: https://doi.org/10.20546/ijcmas.2017.608.099


Performance of SD Bioline Syphilis 3.0 for the Diagnosis of Sypilis a UPFR in Immunology of CHU-JRA
Arinomenjanahary Rakotoarisoa1*, Herinjaka Andriamandimbisoa1, Toky Randriamahazo2, Jaonoharimandimby Andrianavalona2, Davidra Rajaonatahiana3 and Andry Rasamindrakotroka3
1Internal Medical Biology,
2Chief Work in Medical Biology,
3Department of Immunology, CHU – JRA, Antananarivo, Madagascar
*Corresponding author
Abstract:

Serology is considered the pillar of the syphilis diagnosis. The limitations of traditional serological methods, the advent and availability of new immunochromatographic tests have led to the widespread application of rapid procedures as syphilis screening tools. However, these tests are not widely evaluated. This study was designed to evaluate the performance of a rapid diagnostic test for syphilis known as SD BIOLINE Syphilis 3.0. We carried out a prospective study at the Paraclinical Training and Research Unit in Immunology at the University Hospital Center in Antananarivo from March to May 2016 (3 months). We used SD BIOLINE Syphilis 3.0 to test a sample. Test performance was evaluated using Treponema pallidum Hemagglutination Assay (TPHA) and Rapid Plasma Reagin (RPR) as the reference standard, sensitivity, specificity, positive and negative predictive values were calculated. We have thirty-two reactive samples and eight non-reactive samples. The sensitivity, specificity, and positive and negative predictive values of SD BIOLINE Syphilis 3.0 were 100%. Keeping in view the high sensitivity and specificity of SD BIOLINE Syphilis 3.0 we conclude that the test can be used as a tool for the syphilis rapid diagnosis and as an alternative to TPHA for the detection of antibodies to Treponema pallidum.


Keywords: Non-treponemal tests, Fast, Serodiagnosis, Syphilis, Treponemal tests.
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How to cite this article:

Arinomenjanahary Rakotoarisoa, Herinjaka Andriamandimbisoa, Toky Randriamahazo, Jaonoharimandimby Andrianavalona, Davidra Rajaonatahiana and Andry Rasamindrakotroka. 2017. Performance of SD Bioline Syphilis 3.0 for the Diagnosis of Sypilis a UPFR in Immunology of CHU-JRAInt.J.Curr.Microbiol.App.Sci. 6(8): 783-788. doi: https://doi.org/10.20546/ijcmas.2017.608.099